Início > Remdesivir N-3

Remdesivir N-3

Obter o preço mais recente >

Preço fob $6,299.00

Origem: China

Cas No: 1191237-69-0

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 1 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

Fornecedor:

Condições de pagamento:

* Envie um inquérito para nós

* Diga seu preço
* Iniciar o pedido não significa comprar agora

CAS No.	1191237-69-0	Cat. No.
Name	GS441524,Remdesivir N-3
Synonyms	GS-441524; GS 441524;Remdesivir-metabolite;GS-5734-metabolite; GS5734-metabolite; GS 5734-metabolite;
SMILES	C1=C2C(=NC=NN2C(=C1)C3(C(C(C(O3)CO)O)O)C#N)N
Chemical Name
Formula	C12H13N5O4	M. Wt	291.26
Purity	98%	Storage	Store at 4-8°C
Description	Remdesivir N-3 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations as high as 100 uM and effectively inhibited FIPV replication in cultured CRFK cells and in naturally infected feline peritoneal macrophages at concentrations as low as 1 uM. Note: GS-441524 is an active metabolite of Remdesivir.

Remdesivir N-3 is a small molecule with a scientific name of nucleoside triphosphate competitive inhibitor, which shows strong antiviral activity against many RNA viruses. It is capable to inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytia Viruses, and many others,what is more, it is of low cytotoxicity in a wide range of cell lines.