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Remdesivir N-3

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FOB Price $6,299.00

Origin: China

Cas No: 1191237-69-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 1 mt/month

Lead time: 7 days for OEM, 3 days for ready goods


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  • Products Specification
  • Product Description
  • CAS No. 1191237-69-0 Cat. No.  
    Name GS441524,Remdesivir N-3
    Synonyms GS-441524; GS 441524;Remdesivir-metabolite;GS-5734-metabolite; GS5734-metabolite; GS 5734-metabolite;
    SMILES C1=C2C(=NC=NN2C(=C1)C3(C(C(C(O3)CO)O)O)C#N)N
    Chemical Name  
    Formula C12H13N5O4 M. Wt 291.26
    Purity 98% Storage Store at 4-8°C
    Description Remdesivir N-3 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations as high as 100 uM and effectively inhibited FIPV replication in cultured CRFK cells and in naturally infected feline peritoneal macrophages at concentrations as low as 1 uM. Note: GS-441524 is an active metabolite of Remdesivir.
  • Remdesivir N-3 is a small molecule with a scientific name of nucleoside triphosphate competitive inhibitor, which shows strong antiviral activity against many RNA viruses. It is capable to inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syncytia Viruses, and many others,what is more, it is of low cytotoxicity in a wide range of cell lines.

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