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Fmoc-L-propargylglycine

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Origin: China

Cas No: 198561-07-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 198561-07-8 Formula: C20H17NO4 Molecular Weight: 335.35300

Basic Info

Chemical Name	Fmoc-L-propargylglycine
Synonyms	Fmoc-propargyl-Gly-OH; (S)-2-(Fmoc-amino)-4-pentynoic Acid; (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine;
CAS No.	198561-07-8
Molecular Formula	C20H17NO4
Molecular Weight	335.35300
PSA	75.63000
LogP	3.39250

Properties

Appearance & Physical State	white powder
Density	1.292g/cm3
Boiling Point	576.7ºC at 760 mmHg
Melting Point	175ºC
Flash Point	302.6ºC
Refractive Index	1.618
Storage Condition	2-8ºC
Vapor Pressure	3.84E-14mmHg at 25°C

Safety Info

Safety Statements	S24-S25
Hazard Codes	Xi

Synthesis Route

L-Propargylglycine+9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate→Fmoc-L-propargylglycine
(2S)-tert-butyl 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-ynoate→Fmoc-L-propargylglycine
L-Propargylglycine+N-(9-Fluorenylmethoxycarbonyloxy)succinimide→Fmoc-L-propargylglycine

Precursor

tert-butyl (2R)-2-aminopent-4-ynoate
(2S)-tert-butyl 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-ynoate
9H-fluoren-9-ylmethyl 2,5-dioxopyrrolidine-1-carboxylate
N-(9-Fluorenylmethoxycarbonyloxy)succinimide

Downstream Product

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid

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