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Flumethasone Acetate

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Origin: China

Cas No: 2823-42-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 2823-42-9 Formula: C24H30F2O6 Molecular Weight: 452.48800

    Description

    An anti-inflammatory corticosteroid.

    Basic Info

    Chemical Name Flumethasone Acetate
    Synonyms

    [2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;

    CAS No. 2823-42-9
    Molecular Formula C24H30F2O6
    Molecular Weight 452.48800
    PSA 100.90000
    LogP 2.41450

    Properties

    Density 1.33g/cm3
    Boiling Point 571.5ºC at 760mmHg
    Flash Point 299.4ºC
    Refractive Index 1.56
    Vapor Pressure 1.93E-15mmHg at 25°C

    Synthesis Route

    EINECS 224-953-9+Sodium bicarbonate→Flumethasone Acetate
    6α,9α-Difluor-16α-methyl-11β,17α-dihydroxy-21-acetoxy-3,20-dioxo-Δ4-pregnen→Flumethasone Acetate
    21-acetoxy-6α-fluoro-11β,17-dihydroxy-16α-methyl-pregn-4-ene-3,20-dione→Flumethasone Acetate

    Precursor

    21-acetoxy-3,3-ethanediyldioxy-6β-fluoro-16α-methyl-5α-pregn-17(20)t-ene-5,11β-diol
    EINECS 224-953-9
    21-acetoxy-6α-fluoro-11β,17-dihydroxy-16α-methyl-pregn-4-ene-3,20-dione
    Sodium bicarbonate

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