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filipin III

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Origin: China

Cas No: 480-49-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 480-49-9 Formula: C35H58O11 Molecular Weight: 654.82800

Description

Filipin is a mixture of chemical compounds first isolated by chemists at the Upjohn company in 1955 from the mycelium and culture filtrates of a previously unknown actinomycete, Streptomyces filipinensis. It was discovered in a soil sample collected in the Philippine Islands, hence the name filipin. The isolate possessed potent antifungal activity. It was identified as a polyene macrolide based on its characteristic UV-Vis and IR spectra.

Basic Info

Chemical Name	filipin III
Synonyms	FILIPIN III;
CAS No.	480-49-9
Molecular Formula	C35H58O11
Molecular Weight	654.82800
PSA	208.37000
LogP	1.88800

Properties

Density	1.161g/cm3
Boiling Point	913.9ºC at 760 mmHg
Flash Point	279.3ºC
Refractive Index	1.535
Storage Condition	-20ºC
Vapor Pressure	0mmHg at 25°C

Safety Info

Safety Statements	S26; S36
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

→filipin III
(10S,11R)-11-hydroxy-10-(1,1-dimethylethyl)dimethylsiloxy-2,4,6,8-dodecatetraenal→filipin III
→filipin III

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	17 mg/kg	1.Details of toxic effects not reported other than lethal dose value
-	DNA adduct	-	10 mg/L	-