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FASUDIL

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Origin: China

Cas No: 103745-39-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 103745-39-7 Formula: C14H19Cl2N3O2S Molecular Weight: 364.29100

Description

A potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced contraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho-associated Kinase (ROCK IC50= 10.7 uM).

Basic Info

Chemical Name	FASUDIL
Synonyms	Fasudilum [inn-latin]; H-1077 dihydrochloride; hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine; 1-(5-isoquinolinesulphonyl)-homopiperazine; 1-(5-Isoquinolinesulfonyl)-1H-hexahydro-1,4-diazepine,Dihydrochloride; 1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE; HA 1077,DIHYDROCHLORIDE; HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE; at877; Fasudilum;
CAS No.	103745-39-7
Molecular Formula	C14H19Cl2N3O2S
Molecular Weight	364.29100
PSA	70.68000
LogP	4.17030

Properties

Appearance & Physical State	White crystalline solid
Density	1.289g/cm3
Boiling Point	506.2ºC at 760mmHg
Flash Point	259.9ºC
Vapor Pressure	2.55E-12mmHg at 25°C