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ethyl 6-fluoro-1H-indole-2-carboxylate

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Origin: China

Cas No: 348-37-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 348-37-8 Formula: C11H10FNO2 Molecular Weight: 207.20100

Basic Info

Chemical Name	ethyl 6-fluoro-1H-indole-2-carboxylate
Synonyms	6-Fluorindol-2-ethylcarboxylat; 6-Fluoroindole-2-carboxylic acid ethyl ester; 6-Fluor-indol-2-carbonsaeure-aethylester; 6-fluoro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-fluoroindole-2-carboxylate; 6-Fluor-2-indolcarbonsaeureethylester; ZLC0348;
CAS No.	348-37-8
Molecular Formula	C11H10FNO2
Molecular Weight	207.20100
PSA	42.09000
LogP	2.48370

Properties

Density	1.291g/cm3
Boiling Point	345.9ºC at 760mmHg
Flash Point	163ºC

Safety Info

HS Code	2933990090
Hazard Codes	Xi

Synthesis Route

ethyl pyruvate 3-fluorophenylhydrazone→ethyl 6-fluoro-1H-indole-2-carboxylate+ethyl 4-fluoro-1H-indole-2-carboxylate
Ethyl 3-(4-fluoro-2-nitrophenyl)-2-oxopropanoate→ethyl 6-fluoro-1H-indole-2-carboxylate
ethyl 2-azido-3-(4-fluorophenyl)acrylate→ethyl 6-fluoro-1H-indole-2-carboxylate

Precursor

4-Fluorobenzaldehyde
Ethyl 3-(4-fluoro-2-nitrophenyl)-2-oxopropanoate
ethyl 2-azido-3-(4-fluorophenyl)acrylate
2-Bromo-4-fluorobenzaldehyde

Downstream Product

ethyl 6-fluoro-1-methyl-1H-indole-2-carboxylate
6-Fluoroindole
6-fluoro-1H-indole-2-carboxylic acid
Methyl 6-fluoro-1-methyl-1H-indole-2-carboxylate

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