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ethyl 5-fluoro-1H-indole-2-carboxylate

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Origin: China

Cas No: 348-36-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 348-36-7 Formula: C11H10FNO2 Molecular Weight: 207.20100

Basic Info

Chemical Name	ethyl 5-fluoro-1H-indole-2-carboxylate
Synonyms	ethyl5-fluoro-indole-2-carboxylate; Ethyl 5-fluoro-1H-indole-2-carboxylate; Ethyl 5-fluoroindole-2-carboxylate; 5-Fluoroindole-2-carboxylic acid ethyl ester; ethyl-5-fluoro-1H-indole-2-carboxylate; 2-carbethoxy-5-fluoroindole; 5-fluoro-1H-indole-2-carboxylic acid ethyl ester; 5-fluoroindol-2-carboxylic acid ethyl ester;
CAS No.	348-36-7
Molecular Formula	C11H10FNO2
Molecular Weight	207.20100
PSA	42.09000
LogP	2.48370

Properties

Density	1.491g/cm3
Boiling Point	312ºC at 760mmHg
Melting Point	146-150ºC
Flash Point	142.5ºC
Refractive Index	1.6

Safety Info

Safety Statements	S22-S24/25
HS Code	2933990090
WGK Germany	3
Risk Statements	R36/37/38

Synthesis Route

5-Fluoroindole-2-carboxylic acid→ethyl 5-fluoro-1H-indole-2-carboxylate
ethyl 2-[2-(4-fluorophenyl)hydrazinylidene]propanoate→ethyl 5-fluoro-1H-indole-2-carboxylate
Glycine ethyl ester hydrochloride+2-Bromo-5-fluorobenzaldehyde→ethyl 5-fluoro-1H-indole-2-carboxylate

Precursor

ethyl 2-acetamidoacetate
5-Fluoroindole-2-carboxylic acid
ethyl 2-[2-(4-fluorophenyl)hydrazinylidene]propanoate
2-Bromo-5-fluorobenzaldehyde

Downstream Product

5-Fluoroindole-2-carboxylic acid
1-(5-fluoro-1H-indol-3-yl)-N,N-dimethylmethanamine
Ethyl 5-fluoro-3-formyl-1H-indole-2-carboxylate
Ethyl 5-fluoro-3-iodo-1H-indole-2-carboxylate

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