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ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate

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Origin: China

Cas No: 24683-20-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 24683-20-3 Formula: C11H11NO5S Molecular Weight: 269.27400

Description

Piroxicam impurity E.

Basic Info

Chemical Name	ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
Synonyms	Ethyl (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate; ethyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl) acetate; ethyl (3-oxo-1,2-benzoisothiazol-2(3H)-yl)acetate 1,1-dioxide; Saccharin N-(2-Acetic Acid Ethyl Ester)(Piroxicam Impurity E); N-carbethoxymethyl-1,2-benzisothiazole-1,1-dioxide-3-one; Piroxicam Impurity E; Piroxicam impurity E [EP]; Ethyl 1,2-benzisothiazol-3-one-1,1-dioxide-N-acetate; 2-<1,1,3-Trioxo-1,2-benzoisothiazol-2(3H)-yl>essigsaeure-ethylester; UNII-KN712V27AV; ethyl (1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetate; N-(ethoxycarbonyl)methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide;
CAS No.	24683-20-3
Molecular Formula	C11H11NO5S
Molecular Weight	269.27400
PSA	89.13000
LogP	1.41290

Properties

Density	1.442g/cm3
Boiling Point	441.4ºC at 760 mmHg
Flash Point	220.8ºC
Refractive Index	1.584
Vapor Pressure	5.45E-08mmHg at 25°C

Safety Info

HS Code	2934999090

Synthesis Route

Ethyl bromoacetate+Saccharin→ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
o-Benzoic Sulfimide Sodium Salt+Ethyl chloroacetate→ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate
(1,2-Benzisothiazolin-3-on-2-yl)essigsaeureethylester→ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate

Precursor

o-Benzoic Sulfimide Sodium Salt
Ethyl chloroacetate
(1,2-Benzisothiazolin-3-on-2-yl)essigsaeureethylester
Ethyl bromoacetate

Downstream Product

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ<sup>6</sup>,2-benzothiazine-3-carboxamide
Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
4-Hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]-2H-1,2-benzothia zine-3-carboxamide 1,1-dioxide
4-Hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]-2H-1,2-benzothia zine-3-carboxamide 1,1-dioxide

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