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Picture of (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

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Origin: China

Cas No: 148901-68-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 148901-68-2 Formula: C21H16FNO Molecular Weight: 317.35600

    Basic Info

    Chemical Name (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
    Synonyms

    PT-4;

    CAS No. 148901-68-2
    Molecular Formula C21H16FNO
    Molecular Weight 317.35600
    PSA 29.96000
    LogP 5.13040

    Properties

    Appearance & Physical State yellow powder
    Density 1.257g/cm3
    Boiling Point 491.793ºC at 760 mmHg
    Flash Point 251.228ºC
    Refractive Index 1.675
    Vapor Pressure 0mmHg at 25°C

    Synthesis Route

    (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenenitrile(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
    N-ethylidenecyclohexylamine+2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
    N-tert-butylethanimine+2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

    Precursor

    N-tert-butylethanimine
    N-butylethanimine
    2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde
    N-ethylidenecyclohexylamine

    Downstream Product

    Pitavastatin ethyl ester
    (E,3S,5R)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
    pitavastatin calcium
    Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate

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