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(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

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Origem: China

Cas No: 148901-68-2

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 100 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Especificação de produtos
Descrição do produto

Property

CAS No.: 148901-68-2 Formula: C21H16FNO Molecular Weight: 317.35600

Basic Info

Chemical Name	(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
Synonyms	PT-4;
CAS No.	148901-68-2
Molecular Formula	C21H16FNO
Molecular Weight	317.35600
PSA	29.96000
LogP	5.13040

Properties

Appearance & Physical State	yellow powder
Density	1.257g/cm3
Boiling Point	491.793ºC at 760 mmHg
Flash Point	251.228ºC
Refractive Index	1.675
Vapor Pressure	0mmHg at 25°C

Synthesis Route

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenenitrile→(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
N-ethylidenecyclohexylamine+2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde→(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
N-tert-butylethanimine+2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde→(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

Precursor

N-tert-butylethanimine
N-butylethanimine
2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde
N-ethylidenecyclohexylamine

Downstream Product

Pitavastatin ethyl ester
(E,3S,5R)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
pitavastatin calcium
Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate

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