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Home > All categories> Commodity Chemicals> Inorganic Chemicals> Halides> (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde
Picture of (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde

(E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde

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Origin: China

Cas No: 120578-03-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 120578-03-2 Formula: C18H12ClNO Molecular Weight: 293.74700

    Description

    Intermediate in the production of Leukotriene receptor antagonists.

    Basic Info

    Chemical Name (E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde
    Synonyms

    3-(2-(7-CHLOROQUINOLINE-2-YL)-(E)-VINYL)BENZALDEHYDE;
    3-(2-(7-Chloroquinolin-2-yl)vinyl)benzaldehyde;

    CAS No. 120578-03-2
    Molecular Formula C18H12ClNO
    Molecular Weight 293.74700
    PSA 29.96000
    LogP 4.87110

    Properties

    Appearance & Physical State Pale yellow solid
    Density 1.314g/cm3
    Boiling Point 476.502ºC at 760 mmHg
    Flash Point 241.98ºC
    Refractive Index 1.751
    Vapor Pressure 0mmHg at 25°C

    Synthesis Route

    7-Chloro-2-methylquinoline+m-Phthalaldehyde→(E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde
    7-Chloro-2-methylquinoline→(E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde
    methyl 2-[(3R)-3-acetyloxy-1-bromo-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]benzoate→(E)-3-[2-(7-Chloro-2-quinolinyl)ethenyl]benzaldehyde+trans-3-[2-(7-chloroquinolin-2-yl)ethenyl]benzyl alcohol

    Precursor

    METHYL 2-[(S)-3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-HYDROXYPROPYL]BENZOATE
    m-Phthalaldehyde
    methyl 2-[(3R)-3-acetyloxy-1-bromo-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]benzoate
    (S,E)-methyl 2-(3-acetoxy-3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)benzoate

    Downstream Product

    methyl 2-[(3R)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate
    METHYL 2-[(S)-3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-HYDROXYPROPYL]BENZOATE
    1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]ethanol
    1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]prop-2-en-1-ol

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