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doxapram hydrochloride monohydrate

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Origin: China

Cas No: 7081-53-0

Specification: 99%min

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Supply Ability: 100 mt/month

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CAS No.: 7081-53-0 Formula: C24H33ClN2O3 Molecular Weight: 432.98300

Description

Doxapram Hydrochloride Hydrate acts as a respiratory stimulant, reversing the effects of respiratory depression.

Basic Info

Chemical Name	doxapram hydrochloride monohydrate
Synonyms	Doxapram HCL; Doxapram HCl H2O; AHR 619; Doxapram hydrochloride hydrate; Dopram (TN); Doxapram hydrochloride monohydrate; 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone monohydrochloride monohydrate; 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one,hydrate,hydrochloride; 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloride hydrate;
CAS No.	7081-53-0
Molecular Formula	C24H33ClN2O3
Molecular Weight	432.98300
PSA	42.01000
LogP	3.78680

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intravenous	TDLo - Lowest published toxic dose	Human - man	41 mg/kg/24H-C	1.Liver-hepatitis (hepatocellular necrosis), diffuse
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	261 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	174 mg/kg	1.Behavioral-convulsions or effect on seizure threshold 2.Behavioral-excitement 3.Lungs, Thorax, or Respiration-respiratory stimulation

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