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Picture of DMT-dA(bz) Phosphoramidite

DMT-dA(bz) Phosphoramidite

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Origin: China

Cas No: 98796-53-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 98796-53-3 Formula: C47H52N7O7P Molecular Weight: 857.93200

    Description

    N6-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.

    Basic Info

    Chemical Name DMT-dA(bz) Phosphoramidite
    Synonyms

    5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;
    (2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite;

    CAS No. 98796-53-3
    Molecular Formula C47H52N7O7P
    Molecular Weight 857.93200
    PSA 168.70000
    LogP 9.12618

    Properties

    Storage Condition Store at -20ºC

    Safety Info

    HS Code 2903890090

    Synthesis Route

    O-β-cyanoethyl-N,N,N',N'-tetraisopropylphosphoramidite+N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosineDMT-dA(bz) Phosphoramidite
    Bis(Diisopropylamino)(2-Cyanoethoxy)Phosphine+N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosineDMT-dA(bz) Phosphoramidite
    2-cyanoethyl N,N- diisopropylchlorophosphoramidite+N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosineDMT-dA(bz) Phosphoramidite

    Precursor

    N-(9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((bis(diisopropylamino)phosphanyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
    Bis(Diisopropylamino)(2-Cyanoethoxy)Phosphine
    O-β-cyanoethyl-N,N,N',N'-tetraisopropylphosphoramidite
    N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

    Downstream Product

    N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

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