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diosgenin

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Origin: China

Cas No: 512-04-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
512-04-9
Other Names:
diosgenine
MF:
C27H42O3
EINECS No.:
207-563-3
Place of Origin:
China
Type:
Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Antidote, Antineoplastic Agents, Antiparasitic Agents
Grade Standard:
Medicine Grade
Brand Name:
TOP
Model Number:
THT2237
Purity:
99%min
Appearance:
White Powder
Packaging&Delivery
Packaging Details
1kg/Aluminum foil bag, 25kgs/Fibre drum
Port
Any port of China

Property

CAS No.: 512-04-9 Formula: C27H42O3 Molecular Weight: 414.62100

Description

Diosgenin, a steroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, such as the Kokoro. The sugar-free (aglycone), diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products.

Basic Info

Chemical Name	diosgenin
Synonyms	3β-Hydroxy-5-spirostene; Spirost-5-en-3-ol, (3β,25R)-; DELTA 5,20A,22A,25D-SPIROSTEN-3BETA-OL; Diosgenin;
CAS No.	512-04-9
Molecular Formula	C27H42O3
Molecular Weight	414.62100
PSA	38.69000
LogP	5.71390

Properties

Appearance & Physical State	Flaky or needle crystal
Density	1.13 g/cm3
Boiling Point	527.1ºC at 760 mmHg
Melting Point	205-208ºC
Flash Point	272.6ºC
Refractive Index	1.564
Stability	Stable at normal temperatures and pressures.
Storage Condition	Refrigerator

Safety Info

RTECS	WH1450000
Safety Statements	S26; S36/37
HS Code	2932999099
WGK Germany	2
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

3-O-(tert-butyldiphenylsilyl)diosgenin→diosgenin
Trillin→diosgenin
η-diosgenin→diosgenin

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	CP Sil 5 CB	270.	3220.	isothermal

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	>8 gm/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	4872 mg/kg	1.Behavioral-changes in motor activity (specific assay)
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	>8 gm/kg	1.Behavioral-changes in motor activity (specific assay)