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DIMETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE

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Origin: China

Cas No: 122194-07-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 122194-07-4 Formula: C8H20NO2P Molecular Weight: 193.22400

Description

A useful reagent for the efficient phosphorylation of alcohols.

Basic Info

Chemical Name	DIMETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Synonyms	DIMETHYL-N,N-DIISOPROPYLPHOSPHOROAMIDITE; dimethoxy-N,N-diisopropylphosphoramidite; O,O-dimethyl-N,N-diisopropylphosphoramidite; DIMETHYL N N-DIISOPROPYLPHOSPHORAMIDITE; dimethyl-N,N-diisopropylphosphoramidite; N,N-diisopropyl-dimethylphosphoramidite; (DIMETHOXYPHOSPHANYL)BIS(PROPAN-2-YL)AMINE; (dimethoxyphosphanyl)diisopropylamine;
CAS No.	122194-07-4
Molecular Formula	C8H20NO2P
Molecular Weight	193.22400
PSA	35.29000
LogP	2.62490

Properties

Density	0.840 g/mL at 20ºC(lit.)
Boiling Point	54ºC10 mm Hg(lit.)
Flash Point	100ºC
Refractive Index	n20/D 1.420(lit.)
Storage Condition	2-8ºC

Safety Info

Safety Statements	S26
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Sodium methoxide+N,N-Diisopropylmethylphosphoramidic Chloride→DIMETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Methanol+Bis(diisopropylamino)chlorophosphine→DIMETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Methanol+N-dichlorophosphanyl-N-propan-2-ylpropan-2-amine→DIMETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE

Precursor

Bis(diisopropylamino)chlorophosphine
Sodium methoxide
N,N-Diisopropylmethylphosphoramidic Chloride
N-dichlorophosphanyl-N-propan-2-ylpropan-2-amine

Downstream Product

Diisopropylamine
dimethyl propan-2-yl phosphite
Dimethyl phosphonate
dimethyl-(3-methyl-4-methylthiophenyl)phosphite

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