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dehydroepiandrosterone

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Origin: China

Cas No: 53-43-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    53-43-0
    Other Names:
    Dehydroepiandrosterone
    MF:
    C19H28O2
    EINECS No.:
    N/A
    Place of Origin:
    China
    Type:
    Agrochemical Intermediates, Dyestuff Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    98min%
    Brand Name:
    Milliflux
    Model Number:
    Intermediates
    Application:
    Used as intermediate
    Appearance:
    N/A
    Packing:
    1kg/Alu bag or 25kg/Drum
    Assay:
    98.0 %min
    Storage:
    Room Temperature
    Grade:
    EP,USP,CP,JP
    Brand:
    Milliflux Biopharma
    Origin:
    China
    Website:
    www.milliflux.com

    Packaging&Delivery

    Packaging Details
    1kg/Alu bag or 25kg/Drum or as your special request.
    Port
    Any main port in china
    Lead Time:
    Quantity(Boxes)1 - 25>25
    Est. Time(days)3To be negotiated
  • Property

    CAS No.: 53-43-0 Formula: C19H28O2 Molecular Weight: 288.42400

    Description

    Major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.

    Basic Info

    Chemical Name dehydroepiandrosterone
    Synonyms

    DHEA;
    Dehydroisoandrosterone;
    PRASTERONE;
    3β-Hydroxy-5-androsten-17-one;
    17-Hormoforin;
    Deandros;
    5-Androsten-3β-ol-17-one;
    17-Chetovis;
    Dehydroepiandrosterone;
    Diandrone;
    Astenile;
    Psicosterone;
    trans-Dehydroandrosterone;
    Diandron;

    CAS No. 53-43-0
    Molecular Formula C19H28O2
    Molecular Weight 288.42400
    PSA 37.30000
    LogP 3.87920

    Properties

    Appearance & Physical State white fine crystalline powder
    Density 1.12 g/cm3
    Boiling Point 426.7ºC at 760 mmHg
    Melting Point 146-151ºC
    Flash Point 182.1ºC
    Refractive Index 1.56
    Stability Stable under normal temperatures and pressures.
    Storage Condition Hormones

    Safety Info

    RTECS BV8396000
    Safety Statements S24/25
    HS Code 2937290090
    WGK Germany 2
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    pregnenolonedehydroepiandrosterone+17α-hydroxypregnenolone
    pregnenolonedehydroepiandrosterone+androst-5-ene-3β,17β-diol
    Dehydroisoandrosterone 3-acetateTestosterone+dehydroepiandrosterone

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed OV-1 230. 2482. isothermal
    Packed SE-30 225. 2477. isothermal
    Capillary OV-101 230. 2553. isothermal
    Capillary OV-101 230. 2553. isothermal

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat >10 gm/kg 1.Details of toxic effects not reported other than lethal dose value
    Subcutaneous LD50 - Lethal dose, 50 percent kill Rodent - rat 1 gm/kg 1.Details of toxic effects not reported other than lethal dose value
    Oral LD50 - Lethal dose, 50 percent kill Rodent - mouse >10 gm/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    (17Ξ)-spiro[androst-5-en-17,2'-[1,3]oxathiolan]-3β-ol
    (20E)-3beta-Hydroxypregna-5,16-dien-20-one 20-oxime 3-acetate
    Dehydroisoandrosterone 3-acetate
    3beta-(Methoxymethoxy)androst-5-en-17-one

    Downstream Product

    5α-androstane
    4-(2,5-Dimethyl-pyrrol-1-yl)-2-hydroxy-benzoic acid
    (3S,8R,9S,10R,13S,14S)-17-iodo-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
    (1R,3S,5E)-5-[(2E)-2-[(3aS,7aS)-1-(4-hydroxy-4-methylpentoxy)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

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