Home > Chiral Compounds> CP 55,940,(-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol

CP 55,940,(-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol

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Origin: China

Cas No: 83002-04-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 83002-04-4 Formula: C24H40O3 Molecular Weight: 376.57300

Description

CP 55,940 is a cannabinoid which mimics the effects of naturally occurring THC (one of the psychoactive compounds found in cannabis). CP 55,940 was created by Pfizer in 1974 but was never marketed. It is currently used to study the endocannabinoid system.
A study found that CP 55,940 can upregulate 5-HT2A receptors in mice.
CP 55,940 is 45 times more potent than Δ9-THC, and fully antagonized by rimonabant (SR141716A).
CP 55,940 is considered a full agonist at both CB1 and CB2 receptors and has Ki values of 0.58nM and 0.68nM respectively, but is an antagonist at GPR55, the putative "CB3" receptor.
CP 55,940 showed protective effects on rat brain mitochondria upon paraquat exposure.
It also showed neuroprotective effects by reducing intracellular calcium release and reducing hippocampal cell death in cultured neurons subjected to high levels of NMDA.
CP 55,940 induced cell death in NG 108-15 Mouse neuroblastoma x Rat glioma hybrid brain cancer (genetically engineered mouse x rat brain cancer) cells.

Basic Info

Chemical Name	CP 55,940,(-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol
Synonyms	CP 55,940; Sodium phosphate dibasic;
CAS No.	83002-04-4
Molecular Formula	C24H40O3
Molecular Weight	376.57300
PSA	60.69000
LogP	5.65730

Properties

Appearance & Physical State	solid
Density	1.026 g/cm3
Boiling Point	494.4ºC at 760 mmHg
Flash Point	209.2ºC
Storage Condition	2-8ºC

Safety Info

Safety Statements	S22-S24/25

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CP 55,940,(-)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol

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