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betamethasone acetate

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Origin: China

Cas No: 987-24-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 987-24-6 Formula: C24H31FO6 Molecular Weight: 434.49800

    Description

    Betamethasone acetate (BA) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.

    Basic Info

    Chemical Name betamethasone acetate
    Synonyms

    Betamethasone 21-Acetate;

    CAS No. 987-24-6
    Molecular Formula C24H31FO6
    Molecular Weight 434.49800
    PSA 100.90000
    LogP 2.46650

    Properties

    Density 1.3 g/cm3
    Boiling Point 579.4ºC at 760 mmHg
    Melting Point 200-220ºC (dec.)
    Flash Point 304.2ºC
    Refractive Index 1.571
    Storage Condition Refrigerator

    Safety Info

    Safety Statements S22-S36
    WGK Germany 3
    Risk Statements R40
    Hazard Codes Xn

    Synthesis Route

    9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Acetate→betamethasone acetate
    Pregna-1,4,9(11)-triene-3,20-dione, 21-(acetyloxy)-17-hydroxy-16-methyl-, (16β)-→betamethasone acetate
    Pregn-9(11)-en-20-one, 16,17-epoxy-3-hydroxy-, (3β,5α,16α)-→betamethasone acetate

    Precursor

    Pregn-9(11)-en-20-one, 16,17-epoxy-3-hydroxy-, (3β,5α,16α)-
    16β-methyl-3β,17α-dihydroxy-20,20-ethylenedioxy-5α-pregn-9(11)-ene
    9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-Acetate
    16β-methyl-9β,11β-epoxy-17α-hydroxy-1,4-pregnadiene-3,20-dione

    Downstream Product

    betamethasone

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