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Picture of Betadex Sulfobutyl Ether Sodium(β-Cyclodextrin, sulfobutyl ethers, sodium salts)

Betadex Sulfobutyl Ether Sodium(β-Cyclodextrin, sulfobutyl ethers, sodium salts)

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FOB Price $290.00

Origin: China

CasNo: 182410-00-0

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 10 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Description
  • Betadex Sulfobutyl Ether Sodium (USP43)

    ASSAY

    SPECIFICATION

    【IDENTIFICATION】

    A Infraredabsorption

    Complies with SBECD reference

    B Content Analysis

    tR of the major peak complies with SBECD  reference

    C Average Degree of Substitution.

    meets the requirements of the test for Average Degree of Substitution.

    D GENERAL,Sodium

    Positive test for sodium

    【ASSAY】

    THE PERCENTAGE OF BETADEX SULFOBUTYL ETHER SODIUM

    95.0%-105.0%

    【IMPURITIES】

    LIMIT OF BETADEX

    NMT 0.1%

    LIMIT OF 1,4-BUTANE SULTONE

    NMT 0. 5ppm

    LIMIT OF SODIUM CHLORIDE,4-HYDROXYBUTANE-1-SULFONIC ACID,AND BIS(4-SULFOBUTYL) ETHER DISODIUM

    Sodium chloride

    NMT 0.2%

    4-Hydroxybutane-1-sulfonic acid

    NMT 0. 09%

    (4-sulfobutyl) disodium

    NMT 0. 05%

    【SPECIFIC TESTS】

    BACTERIAL ENDOTOXINS TEST

    ≤10EU/g

    Microbial Enumeration Tests

    The total aerobic microbial count

    NMT 100cfu/g

    The total combined molds and yeasts count

    NMT 50cfu/g

    Tests for Specified Microorganisms

    Absence of Escherichia Coli/1g

    Clarity of Solution(30%,w/v)

    The solution is clear ,and essentially free from particles of foreign matter

    AVERAGE DEGREE OF SUBSTITUTION

    6.2-6.9

    Ether Sodium Peaks I -X

    Limit Range(%Peak Area)

    I

    0-0.3

    II

    0-0.9

    III

    0.5-5.0

    IV

    2.0-10.0

    V

    10.0-20.0

    VI

    15.0-25.0

    20.0-30.0

    10.0-25.0

    2.0-12.0

    0-4.0

    PH

    4.0-6.8

    WATERDETERMINATION

    NMT10%

  • Chemical Name

    Captisol

    Synonyms

    CS-0731;Sodium Sulphobutylether-beta-cyclodextrin;SBE-Beta-CD;

    CAS No.

    182410-00-0

    Molecular Formula

    C50H84Na2O41S2

    Molecular Weight

    1451.29000

    PSA

    663.21000

    LogP

    -12.36960

     

    【BETA-CYCLODEXTRIN】Product performance:
    1. Solubilization:
    Neutral, vague and pasty APIs can be effectively combined with butyl betacycline, so that compounds with different solubility in the API can be increased by 10 to 25,000 times.
    2. Convenience:
    Sodium butyl beta cyclodextrin has a good biological seam, which can be injected, exposed, externally used and throat, throat and so on.
    3. Good safety:
    Normally, after an emergency occurs, it can be quickly and completely removed from the accident. In experiments and automobiles, subacute use and toxicity studies provide safe data and are used for drug therapy.
    4. Good stability:
    The absorption of cyclodextrin sodium bromide and beta-cyclodextrin can provide a more beneficial protective environment for the crude drug in its lipophilic cavity, while the hydrophilic surface provides good solubility and solubility.


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