AstaTech (Chengdu) BioPharmaceutical Corp.
AstaTech (Chengdu) Biopharmaceutical Corp., (referred to as “AstaTech-Chengdu”) was registered in 2005, which was evolved from its predecessor AstaTech (Chengdu) Pharmaceutical Company Limited established in 2000. AstaTech-Chengdu has been dedicated to high-quality chemical services for global pharmaceutical R&D and manufacturing enterprises during the last decades.
Headquartered in Chengdu, the western highland of the pharmaceutical industry, AstaTech-Chengdu boasts 12,000-square-meter R&D labs and a pilot plant, as well as an R&D team of 160 researchers (accounts for over 35% of all the employees). We have established R&D labs in the United States and India, and several production bases for advanced intermediates in China to ensure integrated services ranging from lab scale, kilo scale, hundred kilo scale, tons level and hundred tons level, which can satisfy varied customer demands from pre-clinical, clinical to marketed stages. Meanwhile, we are also playing an active part in API services. We have built up a team of over 20 scientists focusing on the development of APIs with high technology barriers, and our GMP production base for APIs will be in operation soon.
Thiophosgene Platform
l Thiophosgene generation
l Thiphogene application
Grignard Reaction
l Boronic acids preparation
l Coupling by Grignard reagent
l Aldehyde preparation
Tetrazole and Azidation
l Tetrazole synthesis
Hydrogenation and Reduction
l Reduction of carbon-carbon double and triple bound even under high pressure
l Reduction of nitro group and so on
l Deprotection
Cyanation
l Formation of cyano group
l Active leaving groups submitted by cyano group
Coupling Technology
l >100 Boronic acids/Biphenyl compounds
l Suzuki, Heck, Hiyama, Negishi, Kumada coupling and so on
Chiral Technology
l Chiral pool synthesis
l Asymmetric catalytic reaction
l Chiral sulfinamide template
l Chiral Catalytic Hydrogenation
l Biocatalysis
Ozonolysis
l Commercial scale ozonolysis
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