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alendronic acid

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Origin: China

Cas No: 66376-36-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details

CAS No.:: 66376-36-1

Other Names:: ABDP, Alendronic acid

MF:: C4H13NO7P2

EINECS No.:: N/M

Place of Origin:: Shandong, China

Type:: treatment of osteoporosis

Grade Standard:: Medicine Grade

Usage:: Animal Pharmaceuticals, Animal Pharmaceuticals

Brand Name:: sigoma

Model Number:: Hot

Purity:: 99% min, 99%

CAS:: 66376-36-1

MW:: 249.1

Grade:: Phamaceutical Grade

Shelf life:: 2 Years

Assay:: HPLC 99%

Boiling point:: 616.7±65.0 °C(Predicted)

Melting point:: 230-235°C

Sample:: Availiable

Packaging&Delivery

Packaging Details: 25kg/drum,1kg/bag or according to customer request

Port: Qingdao port

Lead Time:

Quantity(Kilograms)	1 - 100000	>100000
Est. Time(days)	3	To be negotiated

Products Description

Product name	Alendronic acid
Cas number	66376-36-1
Molecular formula	C4H13NO7P2
Molecular weight	249.1
Appearance	White Crystalline Powder
Melting point	230-235ºC
Boiling point	616.7ºC at 760 mmHg
Relative density	1.857 g/cm3

Property

CAS No.: 66376-36-1 Formula: C4H13NO7P2 Molecular Weight: 249.09600

Basic Info

Chemical Name	alendronic acid
Synonyms	(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid; (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;
CAS No.	66376-36-1
Molecular Formula	C4H13NO7P2
Molecular Weight	249.09600
PSA	180.93000
LogP	-0.57290

Properties

Appearance & Physical State	White Crystalline Powder
Density	1.857 g/cm3
Boiling Point	616.7ºC at 760 mmHg
Melting Point	230-235ºC
Flash Point	326.7ºC

Safety Info

RTECS	SZ6521833
HS Code	2931900090

Synthesis Route

γ-aminobutyric acid→alendronic acid
[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid→alendronic acid
N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid→alendronic acid

Precursor

pyrrolidin-2-one
γ-aminobutyric acid
alendronate sodium trihydrate
N-hydroxysuccinimide ester of 4-(tert-butoxycarbonylamino)butyric acid

Downstream Product

alendronate sodium trihydrate

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