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ACETYLACONITINE

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Origin: China

Cas No: 77181-26-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 77181-26-1 Formula: C36H49NO12 Molecular Weight: 687.77400

    Description

    Acetylaconitine is a diterpenoid alkaloid used in analgesia in rats for the treatment of chronic pain and rheumatoid arthritis.

    Basic Info

    Chemical Name ACETYLACONITINE
    Synonyms

    3-acetylaconitine;

    CAS No. 77181-26-1
    Molecular Formula C36H49NO12
    Molecular Weight 687.77400
    PSA 159.52000
    LogP 1.15680

    Properties

    Density 1.36 g/cm3
    Boiling Point 715.9ºC at 760 mmHg

    Synthesis Route

    Acetic anhydride+aconitineACETYLACONITINE

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 2300 ug/kg 1.Behavioral-convulsions or effect on seizure threshold
    2.Behavioral-muscle weakness
    3.Lungs, Thorax, or Respiration-other changes
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 310 ug/kg 1.Behavioral-convulsions or effect on seizure threshold
    2.Behavioral-muscle weakness
    3.Lungs, Thorax, or Respiration-other changes
    Subcutaneous LD50 - Lethal dose, 50 percent kill Rodent - rat 490 ug/kg 1.Behavioral-convulsions or effect on seizure threshold
    2.Behavioral-muscle weakness
    3.Lungs, Thorax, or Respiration-other changes

    Precursor

    Acetic anhydride
    aconitine

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