CAS No.: 566-19-8 Formula: C19H26O3 Molecular Weight: 302.40800
7-Ketodehydroepiandrosterone (7-keto-DHEA), also known as 7-oxoprasterone, is a steroid produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). 7-Keto is not directly converted to testosterone or estrogen, and has thus been investigated as a potentially more useful relative of DHEA. It is often used as the acetate ester prodrug 7-Keto-DHEA acetate.
While in vitro and animal studies have suggested potential uses for 7-Keto in humans, there is currently limited scientific evidence to support its use as a weight-loss aid, muscle-builder, immune stimulant, or for any other clinical use. One randomized, placebo-controlled research study on dieting and exercising healthy overweight individuals found 7-keto significantly increased body-weight loss and fat-loss. 7-Keto is marketed as a dietary supplement with the implication that it may accelerate weight loss, increase metabolism, enhance memory, or prevent age-related changes. When used in a topical (skin lotion) product 7-Keto caused long-lasting changes in the body's levels of testosterone, epitestosterone, estradiol, and other steroid hormones. Researchers have raised concern that supplements may trigger positive tests for performance-enhancing drugs.
The World Anti-Doping Agency lists 7-keto DHEA as a prohibited anabolic agent.
Chemical Name | 7-Keto Dehydro Epiandrosterone |
Synonyms | 7-Keto-dehydroepiandrosterone; |
CAS No. | 566-19-8 |
Molecular Formula | C19H26O3 |
Molecular Weight | 302.40800 |
PSA | 54.37000 |
LogP | 3.05820 |
Appearance & Physical State | White powder |
Density | 1.19 g/cm3 |
Boiling Point | 477.1ºC at 760 mmHg |
Melting Point | 240.0-244.0ºC |
Flash Point | 256.5ºC |
Refractive Index | 1.569 |
5-androsten-7,17-dione-3β-ol 17-ethylene ketal→7-Keto Dehydro Epiandrosterone
dehydroepiandrosterone→7-Keto Dehydro Epiandrosterone
dehydroepiandrosterone→7-Keto Dehydro Epiandrosterone+(3S,7R,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
(3S,7R,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
dehydroepiandrosterone
Dehydroisoandrosterone 3-acetate
5-androsten-7,17-dione-3β-ol 17-ethylene ketal
3β-(2-tetrahydropyranyloxy)-androst-5-ene-7,17-dione
ANDROST-5-EN-3B ,7,17B -TRIOL
[(8R,9S,10R,13S,14S)-10,13-dimethyl-7,17-dioxo-2,3,4,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
(3S,10R,13S,17S)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one