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6-Bromooxindole

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Origin: China

Cas No: 99365-40-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    99365-40-9
    Other Names:
    6-Bromo-1,3-dihydro-2H-indol-2-one
    MF:
    C8H6BrNO
    EINECS No.:
    800-899-7
    Place of Origin:
    Hubei, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    98%min
    Brand Name:
    Fortunachem
    Model Number:
    Fortuna
    Application:
    Pharmaceutical Intermediates
    Appearance:
    White to yellow powder
    Melting point:
    174-176°C

    Packaging&Delivery

    Packaging Details
    1g~1kg/foil bag, 25kg/drum
    Port
    Any port of China

  • Property

    CAS No.: 99365-40-9 Formula: C8H6BrNO Molecular Weight: 212.04300

    Description

    An indolinone derivative used for the preparation of p38α inhibitors as potential antiinflammatories.

    Basic Info

    Chemical Name 6-Bromooxindole
    Synonyms

    6-Bromo-1,3-dihydro-2H-indol-2-one;

    CAS No. 99365-40-9
    Molecular Formula C8H6BrNO
    Molecular Weight 212.04300
    PSA 29.10000
    LogP 2.08170

    Properties

    Appearance & Physical State light yelllow crystal
    Density 1.666g/cm3
    Boiling Point 343.6ºC at 760mmHg
    Melting Point 217-221ºC
    Flash Point 161.6ºC
    Refractive Index 1.698

    Safety Info

    Safety Statements S26; S36/37/39
    HS Code 2933790090
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    4-Bromo-2-nitrophenylacetic Acid→6-Bromooxindole
    6-bromo-1H-indole-2,3-dione→6-Bromooxindole
    4-Bromo-2-nitrophenylacetic Acid+zinc atom→6-Bromooxindole

    Precursor

    dimethyl 2-(4-bromo-2-nitrophenyl)malonate
    diethyl 2-(4-bromo-2-nitrophenyl)propanedioate
    zinc atom
    6-bromo-1H-indole-2,3-dione

    Downstream Product

    6-Cyanooxindole
    6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
    6-(4-fluorophenyl)-1,3-dihydroindol-2-one
    6'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one

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