Home > Chiral Compounds> 5,6,7,8-tetrahydrofolic acid

5,6,7,8-tetrahydrofolic acid

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Origin: China

Cas No: 135-16-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 135-16-0 Formula: C19H23N7O6 Molecular Weight: 445.42900

Description

Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.

Basic Info

Chemical Name	5,6,7,8-tetrahydrofolic acid
Synonyms	l-amino)benzoyl); 5,6,7,8-Tetrahydrofolic acid; (6RS)-5,6,7,8-Tetrahydro-L-folsaeure; (6S)-Thfa; TETRAHYDROFOLIC ACID; (6S)-Tetrahydrofolic acid; 5,6,7,8-tetrahydrofolicacid; tetrahydropteroylglutamicacid; L-5,6,7,8-Tetrahydrofolic acid; Tetrahydrofolic acide; Tetrahydropteroylglutaamic acid; (6R,6S)-tetrahydrofolic acid;
CAS No.	135-16-0
Molecular Formula	C19H23N7O6
Molecular Weight	445.42900
PSA	211.56000
LogP	1.03910

Properties

Density	1.7g/cm3
Refractive Index	1.762
Storage Condition	-20ºC

Safety Info

HS Code	2933990090

Synthesis Route

N-[4-[[2(R)-amino-3-[(2,5-diamino-4(3H)-oxopyrimidin-6-yl)amino]propyl]amino]benzoyl]-L-glutamic acid→5,6,7,8-tetrahydrofolic acid+(S)-2-(4-(((S)-2-amino-3-((2-amino-5-hydroxy-6-oxo-1,6-dihydropyrimidin-4-yl)amino)propyl)amino)benzamido)pentanedioic acid
Folic acid→5,6,7,8-tetrahydrofolic acid
(4-(((2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzoyl)-D-glutamic acid→5,6,7,8-tetrahydrofolic acid

Precursor

(4-(((2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzoyl)-D-glutamic acid
dihydrofolic acid
Folic acid

Downstream Product

2-[[4-[(2-amino-5-carbamoyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
2-[[4-[[2-amino-5-(ethylcarbamothioyl)-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
10-formyldihydrofolic acid
2-[[4-[[2-amino-5-(2-chloroethylcarbamoyl)-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid

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