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5-iodouracil

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Origin: China

Cas No: 696-07-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    696-07-1
    Other Names:
    5-Iodouracil
    MF:
    C4H3IN2O2
    EINECS No.:
    211-788-2
    Place of Origin:
    Hubei, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    99% min
    Brand Name:
    Fortunachem
    Model Number:
    Fortuna
    Application:
    Pharmaceutical Intermediates
    Appearance:
    White Powder
    Molecular Weight:
    237.98
    Melting point:
    274-276 °C (dec.)(lit.)
    Storage temp:
    0-6°C

    Packaging&Delivery

    Packaging Details
    1kg/foil bag; 25kg/fiber drum
    Port
    Any port of China
    Lead Time:
    Quantity(Kilograms)1 - 2526 - 500>500
    Est. Time(days)37To be negotiated

  • Property

    CAS No.: 696-07-1 Formula: C4H3IN2O2 Molecular Weight: 237.98300

    Description

    5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.

    Basic Info

    Chemical Name 5-iodouracil
    Synonyms

    5-iodopyriMidine-2.4-diol;
    5-iodo uracil;
    4-iodouracil;
    5-Iodouracil;
    5-iodo-uraci;
    5-iodo-2,4-dioxopyrimidine;
    5-iodine uracil;
    5-iodopyrimidine-2,4(1H,3H)-dione;
    2,4(1H,3H)-Pyrimidinedione, 5-iodo-;
    5IU;
    5-IODOURACIL extrapure;

    CAS No. 696-07-1
    Molecular Formula C4H3IN2O2
    Molecular Weight 237.98300
    PSA 66.24000
    LogP 0.49240

    Properties

    Appearance & Physical State silvery white or off white crystalline powder
    Density 2.39 g/cm3
    Boiling Point 401ºC
    Melting Point 270-274ºC
    Refractive Index 1.705
    Water Solubility SOLUBLE IN COLD WATER
    Stability Stable under normal temperatures and pressures.
    Storage Condition 0-6ºC

    Safety Info

    RTECS YR0525000
    Safety Statements S53-S22-S26-S36/37/39-S45
    HS Code 2933599090
    WGK Germany 3
    RIDADR UN 2811
    Risk Statements R46; R20/21/22; R36/37/38
    Hazard Codes T
    Caution Statement P261; P280; P305 + P351 + P338
    Hazard Declaration H302; H312; H315; H319; H332; H335
    Symbol GHS07
    Signal Word Warning

    Synthesis Route

    5-iodo-2-methylsulfanyl-1H-pyrimidin-6-one→Uracil+5-iodouracil
    5-iodo-2'-deoxyuridine→(2R,4S,5R)-5-(hydroxymethyl)oxolane-2,4-diol+5-iodouracil
    Uracil→5-iodouracil

    Precursor

    5-Iodo-2,4-dimethoxypyrimidine
    2,4-Dimethoxypyrimidine
    5-amino-1H-pyrimidine-2,4-dione
    1,3-bis(benzyloxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione

    Downstream Product

    5-ethenyl-1H-pyrimidine-2,4-dione
    5-iodo-2'-deoxyuridine
    thymine
    5-selenophen-2-yl-1H-pyrimidine-2,4-dione

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