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Home > All categories> Commodity Chemicals> Inorganic Chemicals> Halides> (5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
Picture of (5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane

(5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane

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Origin: China

Cas No: 17242-85-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 17242-85-2 Formula: C10H19FN2O2Si2 Molecular Weight: 274.43900

    Basic Info

    Chemical Name (5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
    Synonyms

    5-fluoro-2,4-bis(trimethylsilyloxy)pyrimidine;
    2,4-di-(trimethylsilyloxy)-5-fluoropyrimidine;
    2,4-Bis(trimethylsilyl)-5-fluorouracil;
    Uracil,5-fluoro,TMS;
    5-Fluorouracil,TMS;
    O,O'-bis(TMS)-5-fluorouracil;
    PC1258;
    2,4-bis(trimethylsilyloxy)-5-fluoropyrimidine;

    CAS No. 17242-85-2
    Molecular Formula C10H19FN2O2Si2
    Molecular Weight 274.43900
    PSA 44.24000
    LogP 3.04310

    Properties

    Density 1.05
    Boiling Point 266.5ºC at 760mmHg
    Flash Point 115ºC
    Refractive Index 1.459
    Vapor Pressure 0.0142mmHg at 25°C

    Safety Info

    Hazard Class 3
    Safety Statements S36/37
    HS Code 2933599090
    Packing Group III
    RIDADR UN 1992
    Risk Statements R10; R20/21/22
    Hazard Codes F

    Synthesis Route

    chlorotrimethylsilane+5-fluorouracil→(5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
    5-fluorouracil+hexamethyldisilazane→(5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
    5-fluorouracil+hexamethyldisiloxane→(5-fluoro-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed OV-101 160. 1317.9 isothermal
    Packed SE-30 150. 1326. isothermal
    Packed OV-101 150. 1321. isothermal

    Precursor

    5-fluorouracil
    Trimethylsilyl trifluoromethanesulfonate
    hexamethyldisilazane
    hexamethyldisiloxane

    Downstream Product

    1-[(2'-ACETOXYETHOXY)METHYL]-5-FLUOROURACIL
    5-fluorouracil
    Tegafur
    bromo(trimethyl)silane

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