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5-Bromo-2-fluoropyridine-3-carboxaldehyde

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Origin: China

Cas No: 875781-15-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 875781-15-0 Formula: C6H3BrFNO Molecular Weight: 203.99700

Description

5-Bromo-2-fluoro-3-pyridinecarboxaldehyde is used in the synthesis of [2,3-d]pyrimidine derivatives useful as Raf kinase inhibitors. Also used in the preparation of XIa inhibitors.

Basic Info

Chemical Name	5-Bromo-2-fluoropyridine-3-carboxaldehyde
Synonyms	5-bromo-2-fluoropyridine-3-carbaldehyde;
CAS No.	875781-15-0
Molecular Formula	C6H3BrFNO
Molecular Weight	203.99700
PSA	29.96000
LogP	1.79570

Properties

Density	1.778g/cm3
Boiling Point	258.168ºC at 760 mmHg
Flash Point	109.936ºC
Refractive Index	1.591

Safety Info

HS Code	2933399090

Synthesis Route

N-Formylpiperidine+5-Bromo-2-fluoropyridine→5-Bromo-2-fluoropyridine-3-carboxaldehyde
5-Bromo-2-fluoropyridine→5-Bromo-2-fluoropyridine-3-carboxaldehyde
5-Bromo-2-fluoropyridine+Ethyl formate→5-Bromo-2-fluoropyridine-3-carboxaldehyde

Precursor

Ethyl formate
N-Formylpiperidine
5-Bromo-2-fluoropyridine

Downstream Product

6-Bromopyrido[2,3-d]pyrimidin-2-amine
1-(5-bromo-2-fluoropyridin-3-yl)ethanol
5-Bromo-1H-Pyrazolo[3,4-b]Pyridine
1-(5-Bromo-2-fluoropyridin-3-yl)ethanone

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