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Home > Organofluorine Compounds> 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole
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5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole

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Origin: China

Cas No: 188817-13-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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    CAS No.: 188817-13-2 Formula: C17H12ClF3N2O Molecular Weight: 352.73800

    Description

    5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole is used as a cyclooxygenase inhibitors on the angiogenesis and apoptosis.

    Basic Info

    Chemical Name 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole
    Synonyms

    Ionomycin calcium salt;
    Lopac-S-2064;
    5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethyl pyrazole;
    SC560;

    CAS No. 188817-13-2
    Molecular Formula C17H12ClF3N2O
    Molecular Weight 352.73800
    PSA 27.05000
    LogP 5.22010

    Properties

    Density 1.33g/cm3
    Boiling Point 440.6ºC at 760mmHg
    Flash Point 220.3ºC
    Refractive Index 1.563
    Storage Condition 2-8ºC
    Vapor Pressure 1.51E-07mmHg at 25°C

    Safety Info

    Safety Statements S26; S36
    HS Code 2933199090
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    4'-Chloroacetophenone→5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole
    (4-methoxyphenyl)hydrazine,hydrochloride+1-(4-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione→5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole

    Precursor

    4'-Chloroacetophenone
    (4-methoxyphenyl)hydrazine,hydrochloride
    1-(4-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione

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