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4,4‘-Dichlorodiphenyl sulfone

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Origem: China

Cas No: 80-07-9

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

Quick Details
CAS No.:
80-07-9
Other Names:
4,4'-Dichlorodiphenyl sulfone
MF:
C12H8Cl2O2S
EINECS No.:
201-247-9
Place of Origin:
Shandong, China
Type:
Pharmaceutical Intermediates
Purity:
99.0%min
Brand Name:
ZHISHANG CHEM
Model Number:
ZL- 80-07-9
Application:
Fine Chemical Intermediate
Appearance:
White Powder
Boiling point:
250 °C10 mm Hg(lit.)
Molecular weight:
287.16
Melting point:
143-146 °C(lit.)
Density:
1.54g/cm3
Packing:
25kg/drum
Color:
White
Packaging&Delivery
Packaging Details
25kg/drum
Port
shanghai port
Lead Time:
within 5-7 days after receive payment

Property

CAS No.: 80-07-9 Formula: C12H8Cl2O2S Molecular Weight: 287.16200

Description

4,4’-Dichlorodiphenyl Sulfone is an impurity of Dapson, an antibacterial used in the treatment of dermatitis herpetiformis.

Basic Info

Chemical Name	4,4‘-Dichlorodiphenyl sulfone
Synonyms	Benzene, 1,1‘-sulfonylbis[4-chloro-; 1-chloro-4-(4-chlorophenyl)sulfonylbenzene;
CAS No.	80-07-9
Molecular Formula	C12H8Cl2O2S
Molecular Weight	287.16200
PSA	42.52000
LogP	4.90700

Properties

Appearance & Physical State	off-white to tan Crystalline powder
Density	1.54g/cm3
Boiling Point	397ºC
Melting Point	146-151ºC
Flash Point	233ºC
Refractive Index	1.61
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

Safety Info

RTECS	WR3450000
Safety Statements	S26-S37/39
HS Code	29309070
WGK Germany	2
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

5-p-(p-chlorophenylsulphonyl)phenyl-3-mercapto-1,2,4-triazole→4-Chlorophenyl Phenyl Sulfone+4,4‘-Dichlorodiphenyl sulfone
5-p-(p-chlorophenylsulphonyl)phenyl-3-mercapto-1,2,4-triazole→4-Chlorophenyl Phenyl Sulfone+1-chloro-4-phenylsulfanylbenzene
5-p-(p-chlorophenylsulphonyl)phenyl-3-mercapto-1,2,4-triazole→4-Chlorophenyl Phenyl Sulfone+4,4‘-Dichlorodiphenyl sulfone

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Rodent - rat	364 mg/kg/26W-I	1.Brain and Coverings-recordings from specific areas of CNS 2.Liver-liver function tests impaired