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Picture of 4,4‘-Dichlorodiphenyl sulfone

4,4‘-Dichlorodiphenyl sulfone

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Origin: China

Cas No: 80-07-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    80-07-9
    Other Names:
    4,4'-Dichlorodiphenyl sulfone
    MF:
    C12H8Cl2O2S
    EINECS No.:
    201-247-9
    Place of Origin:
    Shandong, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    99.0%min
    Brand Name:
    ZHISHANG CHEM
    Model Number:
    ZL- 80-07-9
    Application:
    Fine Chemical Intermediate
    Appearance:
    White Powder
    Boiling point:
    250 °C10 mm Hg(lit.)
    Molecular weight:
    287.16
    Melting point:
    143-146 °C(lit.)
    Density:
    1.54g/cm3
    Packing:
    25kg/drum
    Color:
    White

    Packaging&Delivery

    Packaging Details
    25kg/drum
    Port
    shanghai port
    Lead Time:
    within 5-7 days after receive payment
  • Property

    CAS No.: 80-07-9 Formula: C12H8Cl2O2S Molecular Weight: 287.16200

    Description

    4,4’-Dichlorodiphenyl Sulfone is an impurity of Dapson, an antibacterial used in the treatment of dermatitis herpetiformis.

    Basic Info

    Chemical Name 4,4‘-Dichlorodiphenyl sulfone
    Synonyms

    Benzene, 1,1‘-sulfonylbis[4-chloro-;
    1-chloro-4-(4-chlorophenyl)sulfonylbenzene;

    CAS No. 80-07-9
    Molecular Formula C12H8Cl2O2S
    Molecular Weight 287.16200
    PSA 42.52000
    LogP 4.90700

    Properties

    Appearance & Physical State off-white to tan Crystalline powder
    Density 1.54g/cm3
    Boiling Point 397ºC
    Melting Point 146-151ºC
    Flash Point 233ºC
    Refractive Index 1.61
    Stability Stable. Combustible. Incompatible with strong oxidizing agents.

    Safety Info

    RTECS WR3450000
    Safety Statements S26-S37/39
    HS Code 29309070
    WGK Germany 2
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    5-p-(p-chlorophenylsulphonyl)phenyl-3-mercapto-1,2,4-triazole4-Chlorophenyl Phenyl Sulfone+4,4‘-Dichlorodiphenyl sulfone
    5-p-(p-chlorophenylsulphonyl)phenyl-3-mercapto-1,2,4-triazole4-Chlorophenyl Phenyl Sulfone+1-chloro-4-phenylsulfanylbenzene
    5-p-(p-chlorophenylsulphonyl)phenyl-3-mercapto-1,2,4-triazole4-Chlorophenyl Phenyl Sulfone+4,4‘-Dichlorodiphenyl sulfone

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral TDLo - Lowest published toxic dose Rodent - rat 364 mg/kg/26W-I 1.Brain and Coverings-recordings from specific areas of CNS
    2.Liver-liver function tests impaired

    Precursor

    1-chloro-4-(4-chlorophenyl)sulfinylbenzene
    4-Chlorobenzenesulfonyl chloride
    Sodium 4-chlorobenzene sulfinate
    chlorobenzene

    Downstream Product

    2,4'-Dihydroxydiphenyl Sulfone
    4,4'-sulfonyldiphenol
    4-Chlorophenyl Phenyl Sulfone
    1,4-dichlorobenzene

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