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4-(Trifluoromethoxy)aniline

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Origin: China

Cas No: 461-82-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
461-82-5
Other Names:
4- threedifluoro Methoxyaniline
MF:
C7H6F3NO
EINECS No.:
207-317-5
Place of Origin:
Jiangsu, China
Type:
Agrochemical Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
>99%
Brand Name:
KPRX
Model Number:
CAS 461-82-5
Application:
Organic synthesis
Appearance:
Clear colorless liquid
Product name:
Manufacturers selling 4-Trifluoromethoxyaniline 461-82-5
Usage:
Agrochemical & Pharmaceutical Intermediates
Name:
4-(Trifluoromethoxy)aniline
Apperance:
Clear colorless liquid
Keyword:
synthesis of fluorine-containing medicine, pesticide intermediates
Description:
intermediate of insecticide
Packaging&Delivery
Packaging Details
20kg/carton
Pallet can be avialable for bulk order.
Port
Shanghai any port of China
Lead Time:
Quantity(Kilograms) 1 - 1000 >1000
Est. Time(days) 15 To be negotiated

Property

CAS No.: 461-82-5 Formula: C7H6F3NO Molecular Weight: 177.12400

Description

4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole, a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.

Basic Info

Chemical Name	4-(Trifluoromethoxy)aniline
Synonyms	4-aminophenyl trifluoromethyl ether; 4-TRIFLUORO METHOXYLAMINE; 4-(trifluoromethoxy)benzeneamine; 4-Trifluoromethoxyaniline; 4-trifluoromethoxy-aniline; Riluzole Related Compound A; 4-trifluoromethoxyaniune; p-Trifluoromethoxyaniline; 4-amino-trifluoromethoxybenzene; 4-Trifluoroethoxyaniline; AMino TrifluoroMethoxybenzene;
CAS No.	461-82-5
Molecular Formula	C7H6F3NO
Molecular Weight	177.12400
PSA	35.25000
LogP	2.74860

Properties

Appearance & Physical State	light yellow liquid
Density	1.31
Boiling Point	73-75ºC (10 mmHg)
Flash Point	80ºC
Refractive Index	1.462-1.464
Stability	Stable under normal temperatures and pressures.
Storage Condition	Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
Vapor Pressure	2.97mmHg at 25°C

Safety Info

Safety Statements	S26-S36/37/39
HS Code	2921420090
WGK Germany	2
RIDADR	UN 2941
Risk Statements	R20/21/22; R36/37/38
Hazard Codes	Xn

Synthesis Route

1-Nitro-4-(trifluoromethoxy)benzene→4-(Trifluoromethoxy)aniline
1-Bromo-4-(trifluoromethoxy)benzene→4-(Trifluoromethoxy)aniline
N-2-propynyl-4-(trifluoromethoxy)benzenamine→4-(Trifluoromethoxy)aniline

Precursor

4-(trichloromethoxy)benzoyl chloride
1-Nitro-4-(trifluoromethoxy)benzene
4-(Trifluoromethoxy)benzamide
1-Bromo-4-(trifluoromethoxy)benzene

Downstream Product

(3S)-4-hydroxy-3-phenyl-6-(trifluoromethoxy)-3H-quinolin-1-ium-2-one
carbonyl cyanide p-trifluoromethoxyphenylhydrazone
4-(Trifluoromethoxy)phenyl isocyanate
3-acetyl-6-(trifluoromethoxy)-1H-benzimidazol-2-one

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