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4-terpineol

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Origin: China

Cas No: 562-74-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 562-74-3 Formula: C10H18O Molecular Weight: 154.24900

Description

Terpinen-4-ol, also known as 4-Terpineol, is an organic compound in the terpene family. Its molecular formula is C10H18O and its molecular weight is 154.24932 g/mol.
Terpinen-4-ol is used in multiple skin related diseases like blepharitis, rosacea, demodex, meibomian gland dysfunction, chalazia and dry eye. It’s also used in eyelid margin diseases. 4-Terpineol has anti-inflammatory, antibacterial and antifungal effect.
It is considered the primary active ingredient of tea tree oil. It is also the compound of highest concentration in the essential oil of nutmeg.; Terpinen-4-ol occurs in Juniperus communis and is thought to be the reason this wood is highly resistant to rot. Norwegian farmers used to exploit this by making fence poles out of juniper. The concentration is higher in the alpine subspecies of juniper, but occurs in both subspecies.

Basic Info

Chemical Name	4-terpineol
Synonyms	3-Cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-; Terpin-4-ol; terpineol-4; 4-Terpineol; FEMA 2248; Terpene-4-ol; Terpine-4-ol; Terpinenol-4; Terpinen-4-ol; Terpinenolu-4; p-menth-1-en-4-ol; 4-TERPINENOL;
CAS No.	562-74-3
Molecular Formula	C10H18O
Molecular Weight	154.24900
PSA	20.23000
LogP	2.50370

Properties

Appearance & Physical State	colourless or pale yellow liquid
Density	0.929
Boiling Point	212ºC
Flash Point	82ºC
Refractive Index	1.476-1.482
Water Solubility	Very slightly soluble
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Storage Condition	Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

RTECS	OT0175110
Safety Statements	26-36-37/39
WGK Germany	2
Risk Statements	R22; R36/37/38
Hazard Codes	Xn
Symbol	GHS07
Hazard Declaration	H302; H315; H319; H335
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

(Z)-3,7-dimethyl-6-oxooct-2-en-1-yl acetate→4-terpineol
1-methyl-4-propan-2-yl-7-oxabicyclo[2.2.1]heptane+limonene→4-terpineol
2,2,6-trimethyl-1-oxaspiro[2.5]oct-5-ene→terpinolene+2-(4-Methylphenyl)propan-2-ol

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Administration onto the skin	Standard Draize test	Rodent - rabbit	500 mg/24H	-
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1300 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intramuscular	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1500 mg/kg	1.Kidney, Ureter, Bladder-urine volume increased