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4-methylumbelliferone

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Origin: China

Cas No: 90-33-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    90-33-5
    Other Names:
    2H-1-Benzopyran, 7-hydroxy-4-methyl-2-oxo-
    MF:
    C10H8O3, C10H8O3
    EINECS No.:
    201-986-7
    Place of Origin:
    Shandong, China
    Type:
    Other
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    zhishang
    Model Number:
    90-33-5
    Purity:
    99%min
    Product Name:
    4-Methylumbelliferone
    CAS:
    90-33-5
    Grade:
    Medical grade
    Appearance:
    White powder
    Assay:
    99.5%
    Melting point:
    188.5-190 °C(lit.)
    storage temp:
    2-8°C
    brand:
    zhishang
    MW:
    176.17

    Packaging&Delivery

    Packaging Details
    25kg/drum, 200kg/drum or according to your demand.
    chinese supplier 99% Medicine Grade Clenbuterol hydrochloride CAS 21898-19-1 with best price
    Port
    Shanghai port
    Lead Time:
    1-2 days after you payment, we have in stock
  • Property

    CAS No.: 90-33-5 Formula: C10H8O3 Molecular Weight: 176.16900

    Description

    Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity.
    Hymecromone is a crystalline solid with a melting point of 194–195°C. It is soluble in methanol and glacial acetic acid.

    Basic Info

    Chemical Name 4-methylumbelliferone
    Synonyms

    LM 94;
    7-hydroxy-4-methyl-coumarin;
    BMU;
    CantabbY;
    Medilla;
    7-hydroxy-4-methyl-chromen-2-one;
    4-Methylumbelliferone;
    Crodimon;
    4-methyl-7-hydroxy coumarin;
    Bilcolic;
    Himecol;
    7-hydroxy-4-methyl-2H-chromen-2-one;
    Eurogale;

    CAS No. 90-33-5
    Molecular Formula C10H8O3
    Molecular Weight 176.16900
    PSA 50.44000
    LogP 1.80700

    Properties

    Appearance & Physical State solid
    Density 1.319 g/cm3
    Boiling Point 377.4ºC at 760 mmHg
    Melting Point 186-191ºC
    Flash Point 174.5ºC
    Water Solubility slightly soluble
    Stability Stable. Combustible. Incompatible with strong oxidizing agents.
    Storage Condition -20ºC Freezer

    Safety Info

    RTECS GN7000000
    Safety Statements S26-S37/39
    WGK Germany 2
    Risk Statements R20/21/22; R36/37/38
    Hazard Codes Xn

    Synthesis Route

    Phenylacetylene+4-methyl-2-oxo-2H-chromen-7-yl trifluoromethanesulfonate4-methylchromen-2-one+4-methylumbelliferone
    (4-methyl-2-oxochromen-7-yl) 3-methylbutanoateisovaleric acid+4-methylumbelliferone
    4-Methylumbelliferyl-alpha-D-galactopyranoside hydrateD-galactopyranose+4-methylumbelliferone

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 3850 mg/kg 1.Sense Organs and Special Senses (Eye)-lacrimation
    2.Sense Organs and Special Senses (Eye)-ptosis
    3.Behavioral-altered sleep time (including change in righting reflex)
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 2550 mg/kg 1.Sense Organs and Special Senses (Eye)-lacrimation
    2.Sense Organs and Special Senses (Eye)-ptosis
    3.Behavioral-altered sleep time (including change in righting reflex)
    Subcutaneous LD50 - Lethal dose, 50 percent kill Rodent - rat 7200 mg/kg 1.Behavioral-somnolence (general depressed activity)
    2.Skin and Appendages-hair

    Precursor

    Ethyl acetoacetate
    resorcinol
    4-methyl-2-oxo-2H-chromen-7-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
    4-methyl-2-oxo-2H-chromen-7-yl trifluoromethanesulfonate

    Downstream Product

    4-methyl-[1]benzofuro[3,2-g]chromen-2-one
    7-hydroxy-4-methyl-8-(piperidin-1-ylmethyl)chromen-2-one
    2,6-Dimethoxybenzaldehyde
    4-METHYLUMBELLIFERYL-N-ACETYL-β-D-GLUCOSAMINIDE

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