Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Intermediates> 4-Hydroxydiphenylamine

4-Hydroxydiphenylamine

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 122-37-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details

CAS No.:: 122-37-2

Other Names:: 4-(phenylamino)-pheno

MF:: C12H11NO

EINECS No.:: 204-538-9

Place of Origin:: Shaanxi, China

Type:: Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates

Purity:: 99%min

Brand Name:: DIDAC

Model Number:: DAC170112

Application:: Pharm/Chem Industries

Appearance:: Liquid Form

Structure Identification:: H-NMR&LC-MS

Identification:: Infrared Absorption

Test method:: HPLC-ESI-MS

Content:: 99.0% to 101.0%

Water:: 0.5% Max.

Sulfated ash:: 0.1% Max.

Heavy metals:: 10ppm Max

Total Impurity:: 0.2% Max.

Assay:: HPLC

Disregard limit:: 0.0005%

Packaging&Delivery

Packaging Details: 25kgs/Drum; 200kgs/Drum

Port: Any main port of China

Products Description

Item	Standard	Test Results
Identification	A.H-NMR:Comply with the structure	Complies
		B.LC-MS:Comply with the structure	Complies
		C.The IR spectrum of sample should be identical with that of reference standard;	Complies
		D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.	Complies
Crystallinity	meets the requirements.	Complies
Loss on drying	≤2.0%	0.19%
Heavy metals	≤10 ppm	<10ppm
Water	≤1.0%	0.1%
Sulphated ash	≤0.5%, determined on 1.0 g.	0.009%
Related substances	Unspecified impurities: for each impurity ≤0.10%	<0.10%
Related substances		Total Impurity ≤0.5%	0.18%
Purity	≥99.0%	99.7%
Assay	99.0%~101.0% (anhydrous substance).	99.8%
Storage	Preserve in well-closed, light-resistant and airtight containers.	Complies

Property

CAS No.: 122-37-2 Formula: C12H11NO Molecular Weight: 185.22200

Description

4-Hydroxydiphenylamine is used as a reactant in the preparation of iron methylisopropylglyoxime dimethylpyridine/dimethylaminopyridine/phenylaminophenol/imidazolidone complexes.

Basic Info

Chemical Name	4-Hydroxydiphenylamine
Synonyms	4-anilinophenol; Phenol, 4-(phenylamino)-; 4-HydroxydiphenylaMine; p-Anilinophenol;
CAS No.	122-37-2
Molecular Formula	C12H11NO
Molecular Weight	185.22200
PSA	32.26000
LogP	3.20880

Properties

Appearance & Physical State	yellowish crystals
Density	1.203 g/cm3
Boiling Point	190ºC
Melting Point	67-73ºC
Flash Point	146.2ºC
Refractive Index	1.67
Vapor Pressure	8.52E-05mmHg at 25°C

Safety Info

RTECS	SJ6950000
Hazard Class	6.1
Safety Statements	S26-S36/37/39
HS Code	2922299090
Packing Group	III
RIDADR	UN2811
Risk Statements	R37/38; R41
Hazard Codes	Xn

Synthesis Route

N,N-diphenylhydroxylamine→Carbazole+4-Hydroxydiphenylamine
Sulfuric acid+N,N-diphenylhydroxylamine→Carbazole+4-Hydroxydiphenylamine
Benzophenone+Benzhydrol→Benzopinacole+4-Hydroxydiphenylamine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Administration into the eye	Standard Draize test	Rodent - rabbit	250 ug/24H	-
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	3300 mg/kg	1.Autonomic Nervous System-other (direct) parasympathomimetic 2.Behavioral-general anesthetic 3.Blood-methemoglobinemia-carboxyhemoglobin
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	2120 mg/kg	1.Details of toxic effects not reported other than lethal dose value