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4-Fluoro-2-Methoxybenzaldehyde

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Origin: China

Cas No: 450-83-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 450-83-9 Formula: C8H7FO2 Molecular Weight: 154.13800

Description

4-Fluoro-2-methoxy-benzaldehyde is used in the synthesis of imidazopyridazinones acting as novel PDE7 inhibitors for application towards Parkinson’s disease treatment.

Basic Info

Chemical Name	4-Fluoro-2-Methoxybenzaldehyde
Synonyms	4-FLUORO-2-METHOXYBENZALDEHYDE; 4-Fluoro-o-anisaldehyde;
CAS No.	450-83-9
Molecular Formula	C8H7FO2
Molecular Weight	154.13800
PSA	26.30000
LogP	1.64680

Properties

Density	1.192g/cm3
Boiling Point	224.6ºC at 760mmHg
Melting Point	55ºC
Flash Point	87.2ºC
Refractive Index	1.525
Vapor Pressure	0.0905mmHg at 25°C

Safety Info

Safety Statements	26-36
HS Code	2913000090
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

N-Formylpiperidine+3-Fluoroanisole→4-Bromo-3-fluoroanisole+2-Fluoro-4-methoxybenzaldehyde
N-Formylpiperidine+3-Fluoroanisole→2-Fluoro-4-methoxybenzaldehyde+2-Bromo-5-fluoroanisole
4-fluoro-2-hydroxybenzaldehyde+iodomethane→4-Fluoro-2-Methoxybenzaldehyde

Precursor

iodomethane
3-Fluorophenol
4-fluoro-2-hydroxybenzaldehyde
dimethyl sulfate

Downstream Product

4-Fluoro-2-Methoxybenzoic Acid
(4-fluoro-2-methoxyphenyl)methanol
4-Fluoro-2-hydroxybenzoic acid

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