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4-(Difluoromethoxy)aniline

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Origin: China

Cas No: 22236-10-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 22236-10-8 Formula: C7H7F2NO Molecular Weight: 159.13300

Basic Info

Chemical Name	4-(Difluoromethoxy)aniline
Synonyms	α,α-Difluoro-p-anisidine; 4-(difluoromethoxy)aniline; 4-(difluormethoxy)anilin; 4-(OCF2H)aniline; 4-difluoromethoxyphenylamine; 4-(difluoromethoxy)benzenamine; p-difluoromethoxyaniline; 4-Amino-α,α-difluoroanisole; 4-difluoromethoxyaniline;
CAS No.	22236-10-8
Molecular Formula	C7H7F2NO
Molecular Weight	159.13300
PSA	35.25000
LogP	2.45140

Properties

Appearance & Physical State	Salmon pink liquid
Density	1.283
Boiling Point	231ºC
Flash Point	>110ºC
Refractive Index	1.505
Vapor Pressure	0.0928mmHg at 25°C

Safety Info

Safety Statements	S26-S36/37
HS Code	2922299090
WGK Germany	2
RIDADR	UN 2811 6
Risk Statements	R22; R36/37/38; R43
Hazard Codes	Xn

Synthesis Route

4-(DIFLUOROMETHOXY)NITROBENZENE→4-(Difluoromethoxy)aniline
1-(Difluoromethoxy)-4-iodobenzene→4-(Difluoromethoxy)aniline
4-(DIFLUOROMETHOXY)NITROBENZENE+zinc atom→4-(Difluoromethoxy)aniline

Precursor

4-(DIFLUOROMETHOXY)NITROBENZENE
2-Chloro-4,6-dimethylpyrimidine
1-(Difluoromethoxy)-4-iodobenzene
zinc atom

Downstream Product

N-[4-(difluoromethoxy)phenyl]acetamide
N-[4-(difluoromethoxy)phenyl]-2-methylquinazolin-4-amine
5-Chloro-1-[(1S)-1-cyclopropylethyl]-3-{[2,6-dichloro-4-(difluoro methoxy)phenyl]amino}-2(1H)-pyrazinone
2-[4-(difluoromethoxy)anilino]benzoic acid

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