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Picture of 4-(diethoxyphosphorylmethyl)benzoic acid

4-(diethoxyphosphorylmethyl)benzoic acid

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Origin: China

Cas No: 28149-48-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 28149-48-6 Formula: C12H17O5P Molecular Weight: 272.23400

    Description

    Used for the preparation of cholesterol acyltransferase-1 (ACAT-1) inhibitors suitable for use as antiarteriosclerotic and anticholesteremic agents.

    Basic Info

    Chemical Name 4-(diethoxyphosphorylmethyl)benzoic acid
    Synonyms

    4-diethoxyphosphinoylmethylbenzoic acid;
    diethyl 4-carboxybenzylphosphonic acid;
    F9995-0119;

    CAS No. 28149-48-6
    Molecular Formula C12H17O5P
    Molecular Weight 272.23400
    PSA 82.64000
    LogP 3.15090

    Synthesis Route

    4-Bromomethylbenzoic acid+Triethyl phosphite4-(diethoxyphosphorylmethyl)benzoic acid
    Methyl 4-(bromomethyl)benzoate+Triethyl phosphite4-(diethoxyphosphorylmethyl)benzoic acid
    4-Bromomethylbenzoic acid4-(diethoxyphosphorylmethyl)benzoic acid

    Precursor

    4-Bromomethylbenzoic acid
    4-(Chloromethyl)benzoic acid
    Triethyl phosphite
    Methyl 4-(bromomethyl)benzoate

    Downstream Product

    N-(4-bromo-2-cyanophenyl)-4-(diethoxyphosphorylmethyl)benzamide
    4-(diethoxyphosphorylmethyl)benzoyl chloride
    ethyl 4-(diethoxyphosphorylmethyl)benzoate
    4-(diethoxyphosphorylmethyl)benzaldehyde

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