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4-Chloro-DL-phenylalanine methyl ester hydrochloride

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Origin: China

Cas No: 14173-40-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 14173-40-1 Formula: C10H13Cl2NO2 Molecular Weight: 250.12200

Description

4-Chloro-DL-phenylalanine methyl ester hydrochloride is a tryptophan hydroxylase (TPH) inhibitor and a serotonin synthesis inhibitor. 4-Chloro-DL-phenylalanine methyl ester hydrochloride is also known to induce memory deficits in rats.

Basic Info

Chemical Name	4-Chloro-DL-phenylalanine methyl ester hydrochloride
Synonyms	4-Chloro-DL-Phe-OMe HCl; methyl 2-amino-3-(4-chlorophenyl)propanoate,hydrochloride; Methyl 2-amino-3-(4-chlorophenyl)propanoate hydrochloride;
CAS No.	14173-40-1
Molecular Formula	C10H13Cl2NO2
Molecular Weight	250.12200
PSA	52.32000
LogP	2.88510

Properties

Appearance & Physical State	white to off-white powder
Boiling Point	296.3ºC at 760 mmHg
Melting Point	184-188ºC
Flash Point	133ºC
Storage Condition	-20ºC

Safety Info

RTECS	AY4452100
Safety Statements	S22-S24/25
HS Code	2922499990
WGK Germany	3

Synthesis Route

(2S)-2-azido-3-(4-chlorophenyl)propionic acid methyl ester→4-Chloro-DL-phenylalanine methyl ester hydrochloride
Methanol+4-Chloro-Phe-OH→4-Chloro-DL-phenylalanine methyl ester hydrochloride
→4-Chloro-DL-phenylalanine methyl ester hydrochloride

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	TDLo - Lowest published toxic dose	Rodent - rat	400 mg/kg,male 4 day(s) pre-mating	1.Reproductive-Fertility-mating performance (e.g. # sperm positive females per # females mated; # copulations per # estrus cycles)