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4-Chloro-6-fluoroquinoline

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Origin: China

Cas No: 391-77-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 391-77-5 Formula: C9H5ClFN Molecular Weight: 181.59400

Basic Info

Chemical Name	4-Chloro-6-fluoroquinoline
Synonyms	4-Chloro-6-Fluoroquinoline; 4-Chlor-6-fluor-chinolin; 4-chloro-6-fluoro-quinoline; 4-chloro-6-fluoromethylquinoline;
CAS No.	391-77-5
Molecular Formula	C9H5ClFN
Molecular Weight	181.59400
PSA	12.89000
LogP	3.02730

Properties

Density	1.366g/cm3
Boiling Point	259.9ºC at 760 mmHg
Melting Point	95 °C
Flash Point	111ºC
Refractive Index	1.626

Safety Info

Hazard Codes	Xi
Hazard Declaration	H302; H315; H318; H335
Symbol	GHS05, GHS07
Caution Statement	P261; P280; P305 + P351 + P338
Signal Word	Danger

Synthesis Route

6-Fluoro-4-hydroxyquinoline→4-Chloro-6-fluoroquinoline
6-FLUORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID→4-Chloro-6-fluoroquinoline
ethyl 6-fluoro-4-oxo-1H-quinoline-3-carboxylate→4-Chloro-6-fluoroquinoline

Precursor

ethyl 6-fluoro-4-oxo-1H-quinoline-3-carboxylate
diethyl 2-[(4-fluoroanilino)methylidene]propanedioate
6-FLUORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
6-Fluoro-4-hydroxyquinoline

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