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Picture of (3R)-3-{(1S)-1-[(1S)-2-methoxy-1-phenylethyl]carbamoyl-2,2-dimethylpropyl}carbamoyl-6-(2-methyl-1,1'-biphenyl-4-yl)hexanoic acid

(3R)-3-{(1S)-1-[(1S)-2-methoxy-1-phenylethyl]carbamoyl-2,2-dimethylpropyl}carbamoyl-6-(2-methyl-1,1'-biphenyl-4-yl)hexanoic acid

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Origin: China

Cas No: 230961-21-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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    CAS No.: 230961-21-4 Formula: C35H44N2O5 Molecular Weight: 572.73400

    Description

    UK 370106 is a selective, insoluble MMP-3 inhibitor used for the topical treatment of chronic dermal ulcers and wound healing wafers.

    Basic Info

    Chemical Name (3R)-3-{(1S)-1-[(1S)-2-methoxy-1-phenylethyl]carbamoyl-2,2-dimethylpropyl}carbamoyl-6-(2-methyl-1,1'-biphenyl-4-yl)hexanoic acid
    Synonyms

    1-Boc-3-hydroxymethyl-pyrrolidine;

    CAS No. 230961-21-4
    Molecular Formula C35H44N2O5
    Molecular Weight 572.73400
    PSA 104.73000
    LogP 6.89220

    Properties

    Density 1.123g/cm3
    Boiling Point 802.689ºC at 760 mmHg
    Flash Point 439.25ºC
    Refractive Index 1.56
    Vapor Pressure 0mmHg at 25°C

    Synthesis Route

    2-Methyl-2-propanyl (3R)-3-{[(2S)-1-{[(1S)-2-methoxy-1-phenylethy l]amino}-3,3-dimethyl-1-oxo-2-butanyl]carbamoyl}-6-(2-methyl-4-bi phenylyl)hexanoate(3R)-3-{(1S)-1-[(1S)-2-methoxy-1-phenylethyl]carbamoyl-2,2-dimethylpropyl}carbamoyl-6-(2-methyl-1,1'-biphenyl-4-yl)hexanoic acid
    4-bromo-2-methyl-1-phenylbenzene(3R)-3-{(1S)-1-[(1S)-2-methoxy-1-phenylethyl]carbamoyl-2,2-dimethylpropyl}carbamoyl-6-(2-methyl-1,1'-biphenyl-4-yl)hexanoic acid
    5-BROMO-2-IODOTOLUENE(3R)-3-{(1S)-1-[(1S)-2-methoxy-1-phenylethyl]carbamoyl-2,2-dimethylpropyl}carbamoyl-6-(2-methyl-1,1'-biphenyl-4-yl)hexanoic acid

    Precursor

    2-Methyl-2-propanyl (3R)-3-{[(2S)-1-{[(1S)-2-methoxy-1-phenylethy l]amino}-3,3-dimethyl-1-oxo-2-butanyl]carbamoyl}-6-(2-methyl-4-bi phenylyl)hexanoate
    5-BROMO-2-IODOTOLUENE
    N-Boc-L-tert-Leucine
    4-bromo-2-methyl-1-phenylbenzene

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