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3,4-Difluorobenzaldehyde

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Origin: China

Cas No: 34036-07-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 34036-07-2 Formula: C7H4F2O Molecular Weight: 142.10300

Description

3,4-Difluorobenzaldehyde is used in the synthesis of fluorine-substituted analogs of Curcumin, as chemopreventive and/or therapeutic agents against cancers and/or against the development of drug-resistant cancer.

Basic Info

Chemical Name	3,4-Difluorobenzaldehyde
Synonyms	4,5-difluorobenzaldehyde; 3,4-diflourobenzaldehyde;
CAS No.	34036-07-2
Molecular Formula	C7H4F2O
Molecular Weight	142.10300
PSA	17.07000
LogP	1.77730

Properties

Appearance & Physical State	Light Yellow Clear Liquid
Density	1.292
Boiling Point	53-55ºC (15 mmHg)
Flash Point	65ºC
Refractive Index	1.499-1.501

Safety Info

Safety Statements	S26-S37/39
HS Code	2913000090
WGK Germany	2
Risk Statements	R36/37/38
Hazard Codes	Xi
Caution Statement	P261; P305 + P351 + P338
Symbol	GHS07
Hazard Declaration	H315; H319; H335
Signal Word	Warning

Synthesis Route

Water+3,4-Difluorotoluene→3,4-Difluorobenzaldehyde
1-Bromo-3,4-difluorobenzene→3,4-Difluorobenzaldehyde
3,4-Difluorotoluene→3,4-Difluorobenzaldehyde

Precursor

N,N-dimethylformamide
Water
Ethyl formate
1-Bromo-3,4-difluorobenzene

Downstream Product

(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
tert-butyl 4-(2-fluoro-4-formylphenyl)piperazine-1-carboxylate
3-fluoro-4-methylsulfonylbenzaldehyde
4-(3,4-difluorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyridine-5-carboxylic acid

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