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3-Pyridinemethanol

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Origin: China

Cas No: 100-55-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    100-55-0
    Other Names:
    Nicotinyl Alcohol
    MF:
    C6H7NO
    EINECS No.:
    202-864-6
    Place of Origin:
    Hebei, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    99%
    Brand Name:
    Chisure
    Model Number:
    CB100-55-0
    Application:
    Pharmaceutical Intermediates
    Appearance:
    Light Yellow Liquid
    Product name:
    3-Pyridinemethanol
    Form:
    Liquid
    Color:
    Light Yellow
    Assay:
    99%
    Density:
    1.124 g/mL
    Melting point:
    -7 °C
    Boiling point:
    154 °C
    Flash point:
    >230 °F
    Storage:
    Cool Dried Storage
    Shelf life:
    2 years

    Packaging&Delivery

    Packaging Details
    200kg/drum or customized, 3-Pyridinemethanol 100-55-0
    Port
    Tianjin, Shanghai, Qingdao
    Lead Time:
    Quantity(Kilograms)1 - 100101 - 500>500
    Est. Time(days)35To be negotiated

  • Property

    CAS No.: 100-55-0 Formula: C6H7NO Molecular Weight: 109.12600

    Description

    Nicotinyl alcohol (pyridylcarbinol) is a niacin derivative used as a hypolipidemic agent and as a vasodilator. It causes flushing and may decrease blood pressure.
    It appears as a crystal that dissolves in water and alcohol with ease, also soluble in eter; melting range 147-148º.; Nicotinic acid is a brief peripheral vasodilator; this compound was made to make its action longer and effective. It provokes cutaneous flushing in head and upper torax with heat, but with no major effects in blood pressure. It is used in peripheral vascular diseases, like arteriosclerosis obliterans, Raynaud's disease, thromboangiitis obliterans (Buerger's disease), arterial embolism, chilblains or migraine associated with vascular spasm.
    Fischer and Tebrock worked with this drug in more than two hundred patients for more than three years, achieving effective improvements, mainly in syntoms related to intermittent claudication, ulcer healing and others.

    Basic Info

    Chemical Name 3-Pyridinemethanol
    Synonyms

    3-pyridinemethanol;
    pyridin-3-ylmethanol;
    Nicotinyl Alcohol;
    3-(Hydroxymethyl)pyridine;

    CAS No. 100-55-0
    Molecular Formula C6H7NO
    Molecular Weight 109.12600
    PSA 33.12000
    LogP 0.57390

    Properties

    Appearance & Physical State clear light yellow to yellow liquid
    Density 1.124
    Boiling Point 266ºC
    Melting Point -7.7ºC
    Flash Point 97.5ºC
    Refractive Index 1.5425-1.5455
    Water Solubility soluble
    Stability Stable under normal temperatures and pressures.
    Storage Condition 2-8ºC
    Vapor Pressure 0.00442mmHg at 25°C

    Safety Info

    RTECS UT4690000
    Safety Statements S24/25
    HS Code 29333999
    WGK Germany 3
    Risk Statements R36/38
    Hazard Codes Xi
    Signal Word Warning
    Symbol GHS07
    Caution Statement P261; P305 + P351 + P338
    Hazard Declaration H315; H319; H335

    Synthesis Route

    (1-oxidopyridin-1-ium-3-yl)methanol→pyridine-3-carbaldehyde+3-Pyridinemethanol
    3-nitrooxymethylpyridine→pyridine-3-carbaldehyde+3-Pyridinemethanol
    Diethyl ether+N,N-Diethylnicotinamide→pyridine-3-carbaldehyde+3-Pyridinemethanol

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - mouse 1 gm/kg 1.Details of toxic effects not reported other than lethal dose value
    Unreported LD50 - Lethal dose, 50 percent kill Rodent - mouse 2 gm/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    5-Bromo-3-pyridinecarboxaldehyde
    2-Bromopyridine-5-carbaldehyde
    Methyl nicotinate
    2-Chloropyridine-5-carbaldehyde

    Downstream Product

    2-(bromomethyl)pyridine,hydrobromide
    (2S)-4-oxo-4-phenylmethoxy-2-(phenylmethoxycarbonylamino)butanoic acid
    3-(Aminomethyl)pyridine
    N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester

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