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Picture of 3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate

3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate

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Origin: China

Cas No: 350797-56-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 350797-56-7 Formula: C22H23N3O4 Molecular Weight: 393.43600

    Description

    3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate is used in the preparation of Silodosin, an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.

    Basic Info

    Chemical Name 3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate
    Synonyms

    CAS No. 350797-56-7
    Molecular Formula C22H23N3O4
    Molecular Weight 393.43600
    PSA 99.15000
    LogP 3.96378

    Safety Info

    HS Code 2933990090

    Synthesis Route

    1-(3-benzoyloxypropyl)-7-formyl-5-(2-nitropropyl)-2,3-dihydroindole3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate
    indoline3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate
    benzoic acid3-[7-cyano-5-(2-nitropropyl)-2,3-dihydroindol-1-yl]propyl benzoate

    Precursor

    indoline
    3-(5-formyl-2,3-dihydroindol-1-yl)propyl benzoate
    1-(3-benzoyloxypropyl)-7-formyl-5-(2-nitropropyl)-2,3-dihydroindole
    benzoic acid

    Downstream Product

    Silodosin
    (R)-1-(3-Hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carbonitrile
    3-{5-[(2R)-2-Aminopropyl]-7-cyano-2,3-dihydro-1H-indol-1-yl}propy l benzoate
    3-[5-[(2R)-2-aminopropyl]-7-cyano-2,3-dihydroindol-1-yl]propyl benzoate,(2R,3R)-2,3-dihydroxybutanedioic acid

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