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(2S,4R)-4-Methylglutamic Acid

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Origin: China

Cas No: 31137-74-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 31137-74-3 Formula: C6H11NO4 Molecular Weight: 161.15600

Description

A highly selective and potent agonist for kainate receptors.

Basic Info

Chemical Name	(2S,4R)-4-Methylglutamic Acid
Synonyms	(2S,4R)-4-Methylglutamic acid; (2S,4R)-2-azaniumyl-4-methylpentanedioate;
CAS No.	31137-74-3
Molecular Formula	C6H11NO4
Molecular Weight	161.15600
PSA	100.62000
LogP	0.20940

Properties

Appearance & Physical State	White
Boiling Point	329.4ºC at 760mmHg
Flash Point	153ºC

Safety Info

HS Code	2922499990
WGK Germany	3

Synthesis Route

4-methyl-2-ketoglutaric acid→(2S,4R)-4-Methylglutamic Acid+(2S,4S)-2-amino-4-methylpentanedioic acid
diethyl (2S,4S)-2-methyl-4-(4-nitrobenzamido)pentanedioate→(2S,4R)-4-Methylglutamic Acid+(2S,4S)-2-amino-4-methylpentanedioic acid
1-(tert-butyl) 2-methyl (2S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate→(2S,4R)-4-Methylglutamic Acid+(2S,4S)-2-amino-4-methylpentanedioic acid

Precursor

Trioctylamine
4-methyl-2-ketoglutaric acid
(2S,4R)-N-t-butoxycarbonyl- 4-methyl glutamic acid

Downstream Product

(D,L)-4-AMINO-2-METHYL-BUTANOIC ACID

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