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(2S,3R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxybutanoic acid

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Origin: China

Cas No: 15260-10-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
15260-10-3
Other Names:
TBOC-L-THREONINE (BZL)
MF:
C16H23NO5
EINECS No.:
239-304-5
Place of Origin:
Shandong, China
Type:
Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99%
Brand Name:
haihang
Model Number:
HHZHYL
Application:
peptide synthesis
Appearance:
White crystalline powder
NAME:
CAS 15260-10-3
Boiling point:
Boiling point
density:
1.152±0.06 g/cm3(Predicted)
pka:
3.50±0.10(Predicted)
Solubility:
0.5mmole in 5ml DMF clearly soluble
Optical Purity:
≤0.3%D-enantionmer
Packaging&Delivery
Packaging Details
1kg/drum;25kg/drum,200kg/drum or as per customer request.
Port
Shanghai Qingdao Tianjin Dalian Huangpu
Lead Time:
Quantity(Kilograms) 1 - 500 >500
Est. Time(days) 5 To be negotiated

Property

CAS No.: 15260-10-3 Formula: C16H23NO5 Molecular Weight: 309.35800

Basic Info

Chemical Name	(2S,3R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxybutanoic acid
Synonyms	Boc-Thr(Bn)-OH; N-Boc-O-benzyl-L-threonine; N-Boc-L-threonine benzyl ether; N-(tert-Butoxycarbonyl)-O-benzyl-L-threonine; (2S,3R)-2-[(tert-butoxy)carbonylamino]-3-(phenylmethoxy)butanoic acid; Boc-L-Thr(Bn)-OH; Boc-Thr(Bzl)-OH; N-(tert-Butoxycarbonyl)-O-benzyl-L-threonine,Boc-O-benzyl-L-threonine; Boc-Thr(OBn)-OH; O-benzyl-N-Boc-threonine; Boc-O-benzyl-L-threonine; Boc-Thr(Bzl); Boc-T(Bzl)-OH;
CAS No.	15260-10-3
Molecular Formula	C16H23NO5
Molecular Weight	309.35800
PSA	84.86000
LogP	2.96050

Properties

Appearance & Physical State	White to off-white crystalline powder
Density	1.152 g/cm3
Boiling Point	461.5ºC at 760 mmHg
Melting Point	112-114ºC
Flash Point	232.9ºC
Stability	Stable under normal temperatures and pressures.
Storage Condition	2-8ºC
Vapor Pressure	1.36E-07mmHg at 25°C

Safety Info

Safety Statements	S22-S24/25
HS Code	2924299090

Synthesis Route

(2S,3R)-2-amino-3-phenylmethoxybutanoic acid+tert-butyl 1,2,2,2-tetrachloroethyl carbonate→(2S,3R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxybutanoic acid
(2S,3R)-(2-(trimethylsilyl)ethoxy)methyl 3-(benzyloxy)-2-((tert-butoxycarbonyl)amino)butanoate→(2S,3R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxybutanoic acid
Boc-L-Threonine+benzyl bromide→(2S,3R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxybutanoic acid

Precursor

Boc-L-Threonine
tert-butyl 1,2,2,2-tetrachloroethyl carbonate
benzyl bromide
(2S,3R)-2-amino-3-phenylmethoxybutanoic acid

Downstream Product

(2S,3R)-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenylmethoxybutanoic acid
CTOP
L-threonine
CTAP

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