Home > Chiral Compounds> (2S)-3-[4-bis(phenylmethoxy)phosphoryloxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

(2S)-3-[4-bis(phenylmethoxy)phosphoryloxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

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Origin: China

Cas No: 134150-51-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 134150-51-9 Formula: C38H34NO8P Molecular Weight: 663.65200

Basic Info

Chemical Name	(2S)-3-[4-bis(phenylmethoxy)phosphoryloxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Synonyms	Fmoc-pTyr-OH; N\|A-Fmoc-O-[bis(benzyloxy)phosphoryl]-L-tyrosine; O-[bis(benzyloxy)phosphoryl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine; Fmoc-Tyr(PO3Bzl2)-OH; N2-<<(9H-Fluoren-9-yl)methoxy>carbonyl>-O4-<bis(benzyloxy)phosphoryl>-L-tyrosine; Fmoc-Tyr(OPO(OBn)2)-OH;
CAS No.	134150-51-9
Molecular Formula	C38H34NO8P
Molecular Weight	663.65200
PSA	130.20000
LogP	8.53240

Properties

Density	1.321g/cm3
Boiling Point	818.9ºC at 760 mmHg
Flash Point	449.1ºC
Refractive Index	1.631
Storage Condition	-20ºC
Vapor Pressure	2.25E-28mmHg at 25°C

Safety Info

WGK Germany	3

Synthesis Route

(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid→(2S)-3-[4-bis(phenylmethoxy)phosphoryloxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
tert-butyldimethylsilyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-tyrosinate→(2S)-3-[4-bis(phenylmethoxy)phosphoryloxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Dibenzyl diethylphosphoramidite,→(2S)-3-[4-bis(phenylmethoxy)phosphoryloxyphenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

Precursor

2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-(tertbutyldimethylsilyloxy)phenyl)propanoic acid
Dibenzyl diethylphosphoramidite,
tert-butyldimethylsilyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-tyrosinate
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid

Downstream Product

2-[9H-fluoren-9-ylmethoxycarbonyl(phosphono)amino]-3-(4-phenylmethoxyphenyl)propanoic acid

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