Home > Chiral Compounds> (2S)-2-amino-3-hydroxy-N-[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide

(2S)-2-amino-3-hydroxy-N-[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide

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Origin: China

Cas No: 181816-48-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 181816-48-8 Formula: C21H26N2O6 Molecular Weight: 402.44100

Description

Ombrabulin was an experimental drug candidate discovered by Ajinomoto and further developed by Sanofi-Aventis. Ombrabulin is a combretastatin A-4 derivative that exerts its antitumor effect by disrupting the formation of blood vessels needed for tumor growth. It was granted orphan drug status by the European Medicines Agency in April 2011. In January 2013, Sanofi said it discontinued development of ombrabulin after disappointing results from phase III clinical trials.

Basic Info

Chemical Name	(2S)-2-amino-3-hydroxy-N-[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide
Synonyms	Ombrabulin; AC7700; AVE 8062;
CAS No.	181816-48-8
Molecular Formula	C21H26N2O6
Molecular Weight	402.44100
PSA	112.27000
LogP	2.92280

Properties

Density	1.258
Boiling Point	648.1ºC at 760 mmHg

Safety Info

HS Code	2924299090

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(2S)-2-amino-3-hydroxy-N-[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide

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