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(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

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Origin: China

Cas No: 35661-39-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 35661-39-3 Formula: C18H17NO4 Molecular Weight: 311.33200

Description

N-Fmoc-L-alanine is an Fmoc-protected form of L-Alanine. L-Alanine used to make in-vivo measurement of glucose and alanine metabolism in studies of patients with diabetes. L-Alanine is a non-essential amino acid for human development and is one of the 20 amino acids encoded by the genetic code.

Basic Info

Chemical Name	(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Synonyms	N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-alanine Hydrate; Fmoc-Ala-OH Hydrate; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid; 9-fluorenylmethoxycarbonyl-Ala-OH; Fmoc-L-alpha-Alanine; FMOC-Ala-OH; Fmoc-L-alanine Hydrate; Fmoc-L-alanine; N-(9-Fluorenylmethoxycarbonyl)-L-alanine,Fmoc-L-alanine; 9-Fmoc-L-alanine; N-Fmoc-L-alanine;
CAS No.	35661-39-3
Molecular Formula	C18H17NO4
Molecular Weight	311.33200
PSA	79.12000
LogP	3.20260

Properties

Appearance & Physical State	White to off-white crystalline powder
Boiling Point	544.1ºC at 760 mmHg
Melting Point	150-154ºC
Flash Point	282.9ºC
Stability	Stable under normal temperatures and pressures.
Storage Condition	2-8ºC

Safety Info

Safety Statements	S24/25
HS Code	2924299090
Risk Statements	R36/37/38

Synthesis Route

(LGACAGL)2+9H-fluoren-9-ylmethyl carbonochloridate→FMOC-Glycine+(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
N-Fmoc-L-alanine methyl ester→(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
L-alanine+N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide→(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

Precursor

L-alanine
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-amino-2-oxoacetimidoyl cyanide
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-oxo-2-(piperidin-1-yl)acetimidoyl cyanide
N-(((9H-fluoren-9-yl)methoxy)carbonyloxy)-2-(ethylamino)-2-oxoacetimidoyl cyanide

Downstream Product

(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]propanoic acid
DSIP
(2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate
Fmoc-Nalpha-methyl-L-alanine

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