Home > Chiral Compounds> (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid

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Origin: China

Cas No: 71989-26-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
71989-26-9
Other Names:
Fmoc-Lys(Boc)-OH
MF:
C26H32N2O6
EINECS No.:
276-256-4
Place of Origin:
Anhui, China
Type:
Vitamins, Amino Acids and Coenzymes
Grade Standard:
Tech Grade
Brand Name:
Leah chem
Model Number:
Leah 71989-26-9
Purity:
99%
Product Name:
N-alpha-FMOC-Nepsilon-BOC-L-Lysine
Synonyms:
Fmoc-Lys(Boc)-OH
CAS:
71989-26-9
EINECS:
276-256-4
Molecular Formula:
C26H32N2O6
Molecular Weight:
468.54
Appearance:
White Powder
Assay:
99%
Certificate:
COA
Brand:
Leah chem
Packaging&Delivery
Packaging Details
25kgs/drum
Port
Shanghai
Lead Time:
Quantity(Grams) 1 - 2000 >2000
Est. Time(days) 2 To be negotiated

Property

CAS No.: 71989-26-9 Formula: C26H32N2O6 Molecular Weight: 468.54200

Description

Fmoc-Lys(Boc)-OH is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.

Basic Info

Chemical Name	(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
Synonyms	Na-Fmoc-Ne-Boc-L-lysine; N\|A-Fmoc-N\|A-Boc-L-lysine; N-alpha-FMOC-Nepsilon-BOC-L-Lysine; N-Fmoc-N'-Boc-L-Lysine; Nepsilon-Boc-Nalpha-Fmoc-L-lysine; N-(9-fluorenyl)methoxycarbonyl-Lys(Boc)-OH; Fmoc-Lys(Boc); Fmoc-Lys(Boc)-OH;
CAS No.	71989-26-9
Molecular Formula	C26H32N2O6
Molecular Weight	468.54200
PSA	113.96000
LogP	5.45510

Properties

Appearance & Physical State	White powder
Density	1.21 g/cm3
Boiling Point	685.7ºC at 760 mmHg
Melting Point	134-137ºC
Flash Point	368.5ºC
Refractive Index	-12 ° (C=1, DMF)
Stability	Stable. Incompatible with strong oxidizing agents.
Storage Condition	2-8ºC

Safety Info

Safety Statements	S24/25
HS Code	2924299090
WGK Germany	3
Hazard Codes	Xi

Synthesis Route

tert-butoxycarbonyl anhydride→(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
L-lysine hydrochloride→(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
Ne-Boc-L-lysine+N-(9-Fluorenylmethoxycarbonyloxy)succinimide→(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid

Precursor

tert-butoxycarbonyl anhydride
Ne-Boc-L-lysine
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
L-lysine hydrochloride

Downstream Product

Fmoc-Lys(Boc)-OPfp
Ne-Boc-L-lysine
9-methylidenefluorene
Gly-His-Lys

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