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Home > All categories> Food and Feed Additives> Feed Additives> Amino acids and small peptides> (2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
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(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid

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Origin: China

Cas No: 2279-15-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 2279-15-4 Formula: C19H18N2O4 Molecular Weight: 338.35700

    Description

    Nα-Cbz-D-tryptophan is an N-Cbz-protected form of D-Tryptophan. D-Tryptophan is an unnatural isomer of L-Tryptophan and is classified as an essential amino acid. D-Tryptophan has been synthesized as part of some potent Oxytocin (Acetate: O878500) antagonists that treat preterm labour.

    Basic Info

    Chemical Name (2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
    Synonyms

    Nalpha-Cbz-D-tryptophan;
    N-Cbz-D-Trp;
    Z-D-Trp-OH;
    Cbz-D-Trp-OH;
    Nα-Cbz-D-tryptophan;
    CBZ-D-TRYPTOPHAN;
    N-Cbz-D-Tryptophan;
    Nα-Carbobenzoxy-D-tryptophan;
    Nalpha-Carbobenzoxy-D-tryptophan;
    (R)-2-(((Benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoic acid;

    CAS No. 2279-15-4
    Molecular Formula C19H18N2O4
    Molecular Weight 338.35700
    PSA 91.42000
    LogP 3.48090

    Properties

    Appearance & Physical State white crystalline powder
    Density 1.341 g/cm3
    Boiling Point 619.1ºC at 760 mmHg
    Melting Point 122-124ºC
    Flash Point 328.2ºC
    Refractive Index 11 ° (C=1, MeOH)
    Storage Condition Store at RT.
    Vapor Pressure 3.46E-16mmHg at 25°C

    Safety Info

    Safety Statements 22-24/25
    HS Code 2933990090

    Synthesis Route

    N-Cbz-DL-Tryptophan→(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid+(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
    Benzyl chloroformate+D-tryptophan→(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
    Ethanol+N-Cbz-DL-Tryptophan→N-benzyloxycarbonyl-L-tryptophan ethyl ester+(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid

    Precursor

    Benzyl chloroformate
    Ethanol

    D-tryptophan

    Downstream Product

    (2R)-2-amino-3-(1H-indol-3-yl)-2-methylpropanoic acid
    D-tryptophan

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