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(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid

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Origem: China

Cas No: 2279-15-4

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 100 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Especificação de produtos
Descrição do produto

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CAS No.: 2279-15-4 Formula: C19H18N2O4 Molecular Weight: 338.35700

Description

Nα-Cbz-D-tryptophan is an N-Cbz-protected form of D-Tryptophan. D-Tryptophan is an unnatural isomer of L-Tryptophan and is classified as an essential amino acid. D-Tryptophan has been synthesized as part of some potent Oxytocin (Acetate: O878500) antagonists that treat preterm labour.

Basic Info

Chemical Name	(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
Synonyms	Nalpha-Cbz-D-tryptophan; N-Cbz-D-Trp; Z-D-Trp-OH; Cbz-D-Trp-OH; Nα-Cbz-D-tryptophan; CBZ-D-TRYPTOPHAN; N-Cbz-D-Tryptophan; Nα-Carbobenzoxy-D-tryptophan; Nalpha-Carbobenzoxy-D-tryptophan; (R)-2-(((Benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoic acid;
CAS No.	2279-15-4
Molecular Formula	C19H18N2O4
Molecular Weight	338.35700
PSA	91.42000
LogP	3.48090

Properties

Appearance & Physical State	white crystalline powder
Density	1.341 g/cm3
Boiling Point	619.1ºC at 760 mmHg
Melting Point	122-124ºC
Flash Point	328.2ºC
Refractive Index	11 ° (C=1, MeOH)
Storage Condition	Store at RT.
Vapor Pressure	3.46E-16mmHg at 25°C

Safety Info

Safety Statements	22-24/25
HS Code	2933990090

Synthesis Route

N-Cbz-DL-Tryptophan→(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid+(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
Benzyl chloroformate+D-tryptophan→(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
Ethanol+N-Cbz-DL-Tryptophan→N-benzyloxycarbonyl-L-tryptophan ethyl ester+(2R)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid

Precursor

Benzyl chloroformate
Ethanol

D-tryptophan

Downstream Product

(2R)-2-amino-3-(1H-indol-3-yl)-2-methylpropanoic acid
D-tryptophan

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