Início > Chiral Compounds> (2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol

(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol

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Origem: China

Cas No: 119302-19-1

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

Quick Details
CAS No.:
119302-19-1
Other Names:
Androstan-17-...
MF:
C23H37NO2
EINECS No.:
1312995-182-4
Place of Origin:
China
Type:
Pharmaceutical Intermediates
Purity:
99%min
Brand Name:
ROYAL PHARM
Model Number:
BP USP EP JP
Application:
Pharmaceutical Intermediates
Appearance:
Powder, Powder
Grade:
Phamaceutical Grade
Density:
1.143 g/cm3
Boiling point:
469.6 degree centigrade at 760 mmHg
Flashing point:
237.8 degree centigrade
Refractive index:
1.569
Vapor pressure:
8.59E-11mmHg at 25 degree centigrade
PSA:
36.00000
LogP:
3.77950
Molecular Weight:
359.54500
Packaging&Delivery
Packaging Details
Inside the PP bag,aluminum foil bag outside
25Kg/drum
Port
China

Property

CAS No.: 119302-19-1 Formula: C23H37NO2 Molecular Weight: 359.54500

Description

(2α,3α,5α,16β,17β)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol is used in the synthesis of rocuronium bromide, which acts as a neuromuscular blocking agent.

Basic Info

Chemical Name	(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol
Synonyms	2,3-Epoxy-1H-cyclopenta[a]phenanthrene,androstan-17-ol; 2,3-DIFLUORO-4-METHYLPHENYLACETIC ACID; 2,3-EPOXY-1H-CYCLOPENTA[A]PHENANTHRENE,ANDROSTAN-17-OL DERIV(9CI); (1R,2S,11R,12S,16S)-2,16-diMethyl-14-(pyrrolidin-1-yl)-5-oxapentacyclo[9.7.0.0^{2,8}.0^{4,6}.0^{12,16}]octadecan-15-ol; Androstan-17-ol,2,3-epoxy-16-(1-pyrrolidinyl); 2A,3A-EPOXY-16B-(1-PYRROLIDINYL)-5A-ANDROSTAN-17B-OL; (2Alpha,3Alpha,5Alpha,16Beta,17Beta)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol; RocuroniuM BroMide InterMediate VI; ANDROSTAN-17-OL,2,3-EPOXY-16-(1-PYRROLIDINYL)-,(2A,3A,5A,16A,17B)-(9CI);
CAS No.	119302-19-1
Molecular Formula	C23H37NO2
Molecular Weight	359.54500
PSA	36.00000
LogP	3.77950

Properties

Density	1.143 g/cm3
Boiling Point	469.6ºC at 760 mmHg
Flash Point	237.8ºC
Refractive Index	1.569
Vapor Pressure	8.59E-11mmHg at 25°C

Synthesis Route

AND017→(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol
AND017→(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol+(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2,16-di(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
AND017+2α,3α-epoxy-16α-(1-pyrrolidinyl)-5α-androstan-17-one→(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol

Precursor

AND017
2α,3α-epoxy-16α-(1-pyrrolidinyl)-5α-androstan-17-one

Downstream Product

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol
(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2,16-di(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol

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